I don't know the situation with your mother but I did want to toss something out. Even now Lupus is so hard to diagnose and often times people are just given medicine after medicine because they think someone is nuts. It might be possible that your mom was dealing with an AI disease that was never diagnosed and treated properly. I promise you that I have felt crazy more times then I can count over the past couple of years
Success is not final, failure is not fatal: it is the courage to continue that counts.