A little under 1 in 10 patients with lupus suffer with another problem of autoimmunity. This is where the body attacks the thyroid gland that controls the body's metabolism. The thyroid gland can either become underactive or overactive. If the gland is overactive, it can cause sweating, anxiety, shaking, heart pounding and weight loss, if underactive the skin becomes dry, weight gain is a problem and you can slow down mentally. Sometimes the thyroid gland (which is found at the front of the neck) can become swollen. A thyroid problem is easily detected with a simple blood test. It is also quite easily treated.
From this site...http://www.uklupus.co.uk/fact17.html
Are your thyroid problems connected to lupus/ai diseases? I'm wondering about that one myself...thyroid trouble is common in my family and I've had sweating, the shakes, and my heart has been pounding now and then so I'm thinking after considering how this disease can attack the thyroid, hmmmm.
Ugh, research is hard work. It really matters how you word things in search engines. Lol. I couldn't find anything until I worded the search differently after 3 or 4 changes. Lol. And after changing it that one time, this is all I could find, how it attacks the thyroid, but I'm wondering if there are other reasons... other than medications, being more inactive/active, diet changes, etc... I just wonder if this disease directly affects metabolism in other ways than the thyroid. I'm going to keep searching.
I have another AI disease called Hashimoto's Disease. the majority of my glands have been attacked. Everytime I have an attack or flare; I have to go to the cancer section at the hospital to be monitored. They can never tell whether it's the AI in action or cancer from the tests.
As for any AI disease effecting metabolism, I think if it attacks the digestive system. It would decrease the body's ability to absorb nutrients. IE it's harder to gain weight and keep it on. The opposite of my no metabolism problems.
Hope this helps,