Since you've had no responses yet, I am just going to provide you with some information about Norvasc for Raynaud's:
Raynaud’s (ray-NODES) phenomenon is characterized by the development of episodes of pallor (white fingers or toes), or cyanosis (blue discoloration) in response to cold exposure or to emotional stress. Raynaud’s can also affect other body parts such as ears, nose, etc. Usually episodes occur as sudden attacks and they are often triggered by rapid changes in the temperature around you. Secondary Raynaud’s phenomenon is less common than the primary form and it is often more serious. Secondary means that patients have an underlying disease or condition that causes Raynaud’s phenomenon. Connective tissue diseases (such as Lupus) are among the most common causes of secondary Raynaud's. Some of these diseases reduce the blood flow to the digits by causing blood vessel walls to thicken and the vessels to constrict too easily.
The goals of treatment are (1) to reduce the number and severity of the attacks, and (2) to prevent tissue damage. It is important that you avoid cold temperatures and practice stress management. Drug therapy is not indicated in every case, but drug therapy may be necessary if the attacks are severe, if the attacks alter the quality of your life, and if the attacks compromise your ability to perform the activities of daily living.
The most common medications are calcium channel blockers such as nifedipine (Procardia XL®) or Amlodipine (Norvasc®). These are a class of drugs that disrupt the conduction of calcium channels. Calcium channel blockers prevent calcium from entering cells of the heart and blood vessel walls, resulting in lower blood pressure. Calcium channel blockers, also called calcium antagonists, relax and widen blood vessels by affecting the muscle cells in the arterial walls. In this way, the drugs are thought to be beneficial in the treatment of Raynaud's.
Many doctors believe that calcium channel blockers should be used as first-line drug treatment for secondary Raynaud's phenomenon, although not all people benefit from the drug, and a large proportion of people have adverse effects, including headache, flushing, hypotension, peripheral oedema, and nausea.
Other drugs that can be used include alpha-adrenergic blockers (Prazosin or Tamsulosin), or local application of nitroglycerine patches or ointment. Other drugs that are useful in some cases include angiotensin receptor blockers (e.g. Losartan), phosphodiesterase 5 inhibitors [e.g. sildenafil (Viagra®)], and selective serotonin reuptake inhibitors (e.g. Fluoxetine). Anti-platelet drugs like aspirin or clopidogrel (Plavix®) are often added to the treatment regime.
I hope that this information has been helpful to you. Please let us know if you need anything further!
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