I have been on Methotrexate for over a year now and skin issues can be a reaction but there are a few things that help me. I will get sores in my mouth, nose and scalp. When this starts to happen I will just increase my folic acid intake just a bit to help with this symptom. My doctor has also prescribed miracle mouthwash for the mouth sores. I will also get itchy too! What gets me through that is benadryl. I will keep that in my system until 48 hours after the injection. I am sorry you are having a yucky reaction and I really help it gets better. If it doesn't get better or even gets a little worse just check in with the doctor and they will be able to tell you if what you are experiencing is normal or if you are having a reaction that will call for you to stop taking the medication all together. Mountaindreamer is right, maybe the injection would be better for you at this point. That is something you could talk to your doctor about. Keep your head up and I will be thinking about you. I am sending you well wishes and gentle hugs
As I grow to understand life less and less,
I learn to love it more and more.
Age 29, Lupus for last 7 years
Medications: Methotrexate, Lyrica, Celebrex, Flexeril, Theophylline, Bactrim, Xopenex, Lisinopril, Ultram