My name is Rob, and I was diagnosed with with SLE in 2004, and MS in 2008. I have the same burning and itching in my hands and feet. It can be so severe that I'll cause bleeding in a futile attempt to scratch the itch away. I'm on plaquenil, and had an IV methylprednisone treatment about a month ago. For me the steroids really helped with the burn/itch. I also use a cortisone cream that my Dr. prescribed, and it also helps. You may want to ask your Dr./Rheumo if there is a topical cream like this that they would recommend. The fatigue can be opressive. Mine is like I'm covered in a lead blanket. The only thing I can do is rest, sleep, and try to wait it out. Mine comes and goes a couple times a week. I also had to stop working. I ran my own business and had to quit and sell the shop. I was becoming a safety hazard in my own shop around the machinery. My mental "fog", and the opressive fatigue made it a fairly easy decision, but I do miss it. I am on full Social Security Disability now. Having understanding friends and family are a very important thing. It sounds like you have a very supportive husband and kids. I can't tell you how much my family has helped me by being understanding of my situation, and my limitations. It hasn't always been that way, so it's really a gift to have supportive peolpe in my life. Anyway, I just wanted to say welcome. There are some great people here, and excellent information from people with many years of experience with Lupus. I'm glad you found us!