Someone with a LOT more knowledge than I will be along soon, but I can tell you what just happened with me last week. I was originally put on 200mg once per day by my PCP. She also sent me to a rheumie. After hearing what had been going on with me, he was very happy that my doc took the initialtive to put me on Plaq., but was dissapointed, because he said that once a day is NOT enough. He doubled my dose last week. I am also on 20mg of prednisone. He hopes that by next monts appt, I will have enough plaquenil in my system to wean off/take lower dose of prednisone.
I DO remember reading here before (I think from Oluwa or Saysusie) that sometimes they will start you on 200 1x day to see if your stomach can handle it (it can cause stomach upset - not at ALL with me). When they determine you can tolerate that dose, they usually will up it to 2x per day. Im pretty sure thats what was said here before, but, as I said, someone with the accurate info will be along shortly.
Are you on prednisone too?
For God has not given us a spirit of fear; but of power, love and a sound mind. 2 Timothy 1:7