I don't think that you would have that much of a reaction for missing the Plaquenil for just 2 days. Plaquenil builds up in your system. You may have been feeling the affects of overdoing it. I hope that you get to feeling better and try not to miss anymore doses of your medication. I take 400mg of Plaquenil in the morning every day. My doctor told me not to split the dosage. Why I don't know, but that is the way I have been taking it for years. I hope that you get to feeling better.
Lupus for many years. Like most of my life. Sjogrens that started at 35 and Scoliosis, Spinal Stenosis, Degenerative Disc Disease, Osteo-Arthritis of the spine, Ankylosing Spondilitis, Periferal Neuropathy, mild CP and now just recently diagnosed with PA. I had a disc replaced in December of 2007.
Plaquenil, Sulindac, Imuran, Celiac diet, Tramadol and B12 shot once a month.