I have been Plaquenil for 14 years and it has not caused any real weight gain for me. It was the Prednisone that caused the weight gain. I have been lucky in that I have never really had any of the bad side affects of the medication and for me it does help. Maybe others can answer more about this.
Lupus for many years. Like most of my life. Sjogrens that started at 35 and Scoliosis, Spinal Stenosis, Degenerative Disc Disease, Osteo-Arthritis of the spine, Ankylosing Spondilitis, Periferal Neuropathy, mild CP and now just recently diagnosed with PA. I had a disc replaced in December of 2007.
Plaquenil, Sulindac, Imuran, Celiac diet, Tramadol and B12 shot once a month.