Plaquenil treats lupus...it works on the immune system. I'm sure your doctor wants you to take the drug for many reasons. Perhaps you should call them and ask why exactly they want you to take it.
I almost refused to take it, but I'm giving it a chance. It takes weeks or months to build up in your system before you will see any changes. That's why I'm still having issues. I've not been on it long enough to say what it is or isn't going to do for me.
The other point is, this may not be the drug for me. It may do nothing at all. In which case it's back to the drawing board, and I suspect it's not going to do anything for me. But I promised to give it untill May. I've been on it since December.