Celebrex is not so much a pain medication as it is a medication for inflammation. Celebrex is in a group of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Celebrex works by reducing hormones that cause inflammation in the body. It is hoped that when the inflammation is reduced, the pain will subside. If this is not the case, then doctors will usually prescribe a medication specifically for pain.
Plaquenil is an anti-rheumatic drug. Plaquenil has beneficial effects on 3 major aspects of lupus; skin rashes, aches & pains and fatigue. It is very effective in the treatment of a whole variety of lupus skin rashes, particularly those found to be worsened by sunlight. Thus it is widely used as first choice (or ‘first line’) treatment in lupus. As well as helping the skin itself, it is often helpful in treating hair loss in lupus. It helps the muscle & joint pains, though in cases where these are severe - such as your case, its effects may be too mild and a pain reliever may have to be prescribed. One of the most successful uses is in fatigue, many patients showing improvement after several weeks’ treatment.
With reference to you night pain, this is probably the arthritic pain of Lupus that is causing you problems. Sometimes a vicious cycle can occur wherein pain prevents you from getting enough sleep, fatigue has hampered you during the day, depression sets in and aggravates the pain, and then sleep is even more disturbed by the pain and depression at night. Daytime activity may lead to night time pain due to the inflammation of the joints and muscles. Also, the amount of disease activity can be directly related to night pain. Unfortunately, night pain is common and many doctors suggest relaxation techniques and hot therapies to help with the pain and to help you sleep. This, again, is probably something that you should discuss with your doctor.
I wish you the best :lol:
Peace and Blessings
Look For The Good and Praise It!