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Thread: Newbie signing in - and a question about Celebrex

  1. #1
    Join Date
    Feb 2004
    Clayton, NC
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    Default Newbie signing in - and a question about Celebrex

    I've just joined the board and I'd like to introduce myself. First of all - I don't have lupus - for what it's worth - I have MCTD -mixed connective tissue disorder - which means I have some lupus symptoms but not enough signs to 'qualify', and I have a negative ANA. My main symptom is pleurisy, and I've had this all my life in a minor manner - bouts that were treatable with anti-inflamatories, and went away in a few weeks. Back in 1996, a series of really bad colds/flu brought on a really bad pleurisy attack that ended with me in the hospital with pleurisy, pericarditis, pneumonia, bleeding ulcers (from NSAIDs). It took a few weeks and another hospital for a doctor to figure out that this was autoimmune, because that negative ANA made them assume it couldn't be. When they pumped me full of prednisone, relief was miraculous.

    Unfortunately, I have been on prednisone ever since, and my rheumatologist has had me try everything in the book to reduce my prednisone use, but nothing has worked. Overall I'm in pretty good shape right now, and have found that regular workouts at the gym (some aerobic and various weight machines) does wonders for me.

    I've been taking Celebrex since it came out. For various reasons, I decided to try life without it last week. Of course, it has been a week of 'drug withdrawal', but now I feel OK, and a workout eases my joint pain more than anything.

    Here is my question: since I stopped the Celebrex, my weight has dropped about 5 pounds, I've been urinating very very frequently, the edema I had every day in my legs is gone. I hadn't notice a weight gain with starting the Celebrex, and I have read that water retention is a not-unheard-of side effect, but I found this much water loss surprising. Has anyone had this kind of experience?

    By the way, I am 62 years old, so at the time of this long episode (my sed rate and CRP tell us that I still need the prednisone - as does chest pain if I try to decrease it) I was 55. Autoimmune diseases are viewed as "belonging" to young women, another thing that threw the doctors off the track.

    Well, I've been long-winded. Hello to all and hope to be around now and then.


  2. #2
    Join Date
    Nov 2001
    Victorville, California
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    Hi Sandra and welcome to our forum. I hope that we can provide you with some answers, support, and just be a place where you can discuss your feelings, your symptoms and know that you are not alone!
    Here is what I found out about Celebrex:
    Celebrex is a non-steroidal anti-inflammatory medicine (NSAID) that is used to reduce pain and inflammation (swelling and soreness). Celebrex is a medicine for:
    relief of osteoarthritis (the arthritis caused by age-related ?wear and tear? on bones and joints)
    relief of rheumatoid arthritis in adults
    management of acute pain in adults (like the short term pain you can get after a dental or surgical operation)
    treatment of menstrual pain (pain during women?s monthly periods) Who should nottake Celebrex?
    Do not take Celebrex if you:
    have had an allergic-type reaction to sulfa medicines
    have had asthma, hives or allergic-type reactions after taking aspirin or other NSAID medicines
    are allergic to Celebrex or to any of the ingredients in Celebrex

    If you have asthma, you may have aspirin-sensitive asthma. If an aspirin-sensitive asthmatic takes aspirin it can cause severe narrowing of the airway (bronchospasm), and even death. Since this type of reaction to aspirin and other NSAID medicines have happened in aspirin-sensitive patients, aspirin-sensitive patients should not take Celebrex.
    Special Warnings with Celebrex:
    Celebrex and other NSAID medicines can cause stomach ulcers that bleed. The chance of this serious problem increases the longer you take Celebrex and with higher doses of Celebrex. Stomach bleeding can also happen suddenly while you take Celebrex. Stop taking Celebrex and call your healthcare provider right away if you get:
    a burning stomach pain
    black bowel movements that look like tar
    vomit that looks like blood or coffee grounds

    Celebrex and other NSAID medicines can cause serious allergic reactions that include swelling of the face, lips, tongue or throat. These allergic reactions may cause problems with breathing, swallowing, and wheezing. Serious allergic skin reactions have also happened.
    General Precautions with Celebrex:
    Celebrex and other NSAID medicines can cause serious problems such as liver damage. Some of the warning signs of liver damage are nausea, vomiting, tiredness, loss of appetite, itching, yellow coloring of skin or eyes, ?flu-like? symptoms and dark urine. If these happen, stop taking Celebrex and call your health care provider right away.
    Celebrex and other NSAID medicines can cause serious kidney problems that include sudden kidney failure or worsening of kidney problems that you already have.
    Celebrex and other NSAID medicines can cause fluid retention (holding of water in your body) and swelling. Fluid retention can be a serious problem if you have high blood pressure or heart failure.
    Tell your health care provider if you:
    are trying to become pregnant, are already pregnant, or are breast-feeding
    have or had angina (chest pain), heart attack or blocked artery in your heart
    have kidney problems
    have liver problems
    have heart failure
    have high blood pressure
    retain fluids (hold extra body water and swell)
    had an allergic reaction to aspirin or other NSAID medicines
    had a serious stomach problem in the past
    have or had any other medical problems or allergies

    Tell your health care provider about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Some medicines may affect how Celebrex works or Celebrex may affect how your other medicines work. Your healthcare provider may have to adjust your dose or watch you closely if you take certain medicines. Celebrex cannot take the place of aspirin for prevention of heart attack or stroke. If you take aspirin for this purpose, do not stop taking aspirin without talking to your doctor.
    What are some possible side effects of Celebrex?(This is NOTa complete list of side effects reported with Celebrex. Your health care provider can discuss with you a more complete list of side effects.)
    In addition to the serious side effects listed above, some common, but less serious side effects with Celebrex include:
    upper respiratory tract infection (a "cold")
    sinus inflammation
    stomach pain

    I hope that this answers your questions about the Drug. If you need anything further, please ask. We are here to help in any way that we can!!
    Peace and Blessings

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