Fatigue is a hallmark of lupus, and one of the things that makes it so difficult to function. My fatigue improved with plaquenil (but it took a long time to really work - 6 to 8 months for me.) Steroids like prednisone really do a number on sleep patterns, for many people. I have never been a very good sleeper, and prednisone has just destroyed my sleep patterns. You'll hear many people on the forum talk about the various meds they take to help them sleep. Talk to your doctor about it. If you aren't sleeping you'll have a difficult time dealing with the fatigue (obviously) but rest is critical for all aspect of lupus. Hope your docs can help you out.
"If you trust Google more than you trust your doctor than maybe it's time to switch doctors."