I have Lupus Nephritis, I was diagnosed three years ago and have completed chemo, prednisone and am still on Plaquenil. I take B-Complex, Flax Oil, Fish Oil, and DhEA everyday. I still feel so tired all the time and am desperately trying to work, but it has become so difficult to do more than 4-5hr. days a week. Financially this kills and I never feel refreshed upon wakening. Does anyone know of anything that helps? I am starting to get really depressed.