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Thread: Newbie

  1. #1
    Join Date
    Oct 2003
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    Default Newbie

    hi you guy's came across this site by accident but am glad I did.

    I was dianosed with SLE when I was 18 (a lotta years ago LOL !!) since then I was told I had Screroderma,Raynaud's and AVN both hips and knees. I'm confused as I was told just a few years ago that there were no signs in my blood tests of the sle but signs of scleroderma!! I thought sle stayed with you for life!

    I was on steroids off and on for years which my specialist thinks causeed the AVN I don't want to alarm people by saying this, but it's what I've been told and have read up on it all saying that AVN can be caused by steroid use.

    Sue I read on one of the pages the symptoms of Fibromyalgia and they are remarkably familiar to me!

    So you guys don't mean to bore you but i could have sle, sclero... or what!!!!

    Take care all you brave people out there

    Jack :?

  2. #2
    Join Date
    Nov 2001
    Victorville, California
    Blog Entries
    Thanked 1,128 Times in 743 Posts


    Hi Jack;
    You could possibly have what is called "Overlap". Scleroderma is a connective tissue disease and can easily overlap with other connective tissue diseases, such as LUPUS, POLYMYOSITIS, AND DERMATOMYOSITIS, SJOGREN'S SYNDROME, RAYNAUD'S SYNDROME, RHEUMATOID ARTHRITIS. This is called "Mixed Connective Tissue Disease (MCTD). Many patients with scleroderma have positive antinuclear antibodies
    What is important for us is that there is one specific type of overlap-syndrome with symptoms of lupus, scleroderma, myositis and rheumatoid arthritis, together with a large quantity of antibodies against a specific antigen (U1RNP). This has been discovered to be a distinct disease, MCTD and is considered a distinct clinical entity. Sjogren's Syndrome is ver common in MCTD.
    Scleroderma is a generalised autoimmune disease that causes tightening and thickening of the connective tissue (sclerosis). Systemic sclerosis usually involves the skin, but sometimes it also affects the gastrointestinal tract, the lungs and the kidneys. At the same time a narrowing of the small blood vessels takes place. Because the hardening of the skin is the most typical symptom of the disease, it is called 'scleroderma'. Since the disease also affects internal organs, the name 'systemic sclerosis' is more precise.
    The skin may show symptoms of scleroderma as well as symptoms of lupus. The fingers my show symptoms of Raynaud's ; muscle inflammation like polymyositis, reduced lung volume, inflammation of the heart like pericarditis, dry mucous membranes like Sjogren's.
    Perhaps you can ask your doctor to test for the presence of anti-U1RNP antibodies in high titer. If your doctor suspects MCTD, come additional tests may have to be run.
    Treatment usually consists of low doses of corticosteroids!
    I hope that I have been helpful! Let me know if you need any more information
    Peace and Blessings

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