Hi LDG, When I was first dx, I was on plaquenil for a year, it really didn't do much for me and I ended up hospitalized unable to move my arms or legs, I was then put on a huge dose of prednisone for a while, it took me a year and a half to taper completely off it. I have been off pred for 6 months now. While on prednisone they started me on methotrexate pills, I believe this is why I was able to get off the prednisone. However, I suffered many side effects from the methotrexate, i was sick to my stomach with a headache and really fatigued for a couple days of the week and I lost a lot of hair (no worries, no baldness or anything). Because of all the stomach trouble my doctor changed me to the methotrexate injections, I've been on this for about 2 months now and I feel hardly any side efffects now. As far as how I feel lupus wise, I still flare but I have gone without the Methotrexate and believe me I feel WAY worse without it, so yes it works, my bloodwork is good too. My pain level was lower with the prednisone though. And this week I'm in a bad flare, hopefully it will go away.
For I know the plans I have for you declares the Lord, plans for good and not evil to give you a future and a hope. Jeremiah 29:11