SLE is irreverisble, however, drug-induced Lupus generally is reversible when the drug is dicontinued. They symptoms of drug-induced lupus generally DO NOT include involvement of the kidneys or the central nervous system.
The drugs that are most commonly associated with drug-induced LUPUS include:
1. Procainamide (Procan, Pronestyl) used for heart rhythm abnormalities.
2. Hydralazine (Apresoline, Apresazide) used for high blood pressure.
3. Quinidine, used for heart rhythm abnormalities
4. Isoniazid (INH) used for tuberculosis
5. Phenytoin (Dilantin) used for confulsive disorders or seizures.
There are other drugs wich may possibly be associated with drug-induced LUPUS (DIL), but there is not definitive proof yet. Experts say that most of the drugs associated with DIL can be safely used in people with SLE or cutaneous lupus (discoidal) IF there are no other alternatives.

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