From what I've read and heard, chemotherapy is only used on the worst cases of Lupus - eminent life-threatening cases. I have never heard of it being used as a standard treatment. Of those treated with chemotherapy, it was given for four days and the bad news is, not everyone went into a remission. The good news was 40% did, and the remissions had lasted as long as five years! Doctors warn that chemotherapy is not a cure, but it's another way of thinking about the worst lupus.