The ANA test is one of many tests used to screen for Lupus. A positive or negative result should not be used to determine if a person does or does not have Lupus. If the patient is displaying symptoms of Lupus and the ANA test is negative, most doctors will then run the following tests: Anti-DNA, anti-Sm, anti-Ro/SSA, anti-La/SSB, and anti-RNP, and will also test other abnormalities present in your specific condition.
There is a condition known as ANA-Negative Lupus and in order to be diagnosed with this, the above listed tests must be positive. It is never critical to say definitively that a given patient does or does not have lupus. What is important is to evaluate your current symptoms, to put your symptoms into an overall context that includes blood tests, duration of symptoms, other illnesses, and medications, and to develop a treatment plan based on the total information rather than on a blood test alone. If you are presenting with symptoms, those symptoms should be treated regardless of the results of your ANA.
I hope that this was helpful. Please let me know if you need anything further
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