Dosage requirements of corticosteroids vary among individuals and the diseases being treated and the time in which you see positive effects varies dependent upon the dosage and the severity of the disease. In general, the lowest effective dose is used in order to treat your symptoms.
Methylprednisolone is used to achieve prompt suppression of inflammation. Examples of inflammatory conditions for which methylprednisolone is used include rheumatoid arthritis, systemic lupus erythematosus, acute gouty arthritis, psoriatic arthritis, ulcerative colitis, and Crohn's disease. Most signs of lupus respond rapidly to corticosteroid treatment. Since you say that your symptoms seem to be worsening, I would suggest that you contact your doctor and advise him/or her of this.
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