I take 1500 mg cellcept twice daily due to an elevated anti ds-dna level which doesn't seem to care what meds or how much I take to control it.
As the cellcept does not seem to be having much effect my ruhemy questioned me at great length to insure I was taking my meds correctly.
According to him the warning/direction to take cellcept an hour before or 2 hours after eating has to do with proper absorption not concerns over possible upset stomach.
In other words if you don't follow the label directions it may not work as well or at all!