When I was first diagnosed, my rheumy put me on plaquenil and pred.
The pred was to work fast, whilst waiting for the plaquenil to take its effect.
After a few months we started to reduce the pred. As the pain and symptoms started to come back ..... then we started mtx.
We started on 2mg on 1 day per week. The dosage was increased as required, as the pred was reduced also. I ended up on 20mg of mtx.
After about 1 1/2 years we cut mtx back, now at 10mg.
My understanding is that pred works quickly and comes out of the system quickly to. There is no " build up" of the medication required.
Mtx does require a build up in our system. It is only a couple of weeks. but it is a build up.
Also mtx is a disease modifying drug.
This means it actually creates a chemical reaction within our system.
My un-doctor description is it is like making a cake.
mix flour, butter and an egg together, and you make a new mixture that can never be separated again. (mtx does this in our system.)
hopefully I have made sense to you.
Last edited by steve.b; 09-17-2013 at 03:05 AM.
When you're stressed, You eat Ice cream, Cake, Chocolate & Sweets. Why? Because stressed spelled backwards is DESSERTS.