Results 1 to 10 of 10

Thread: Indications For Meds Other Than Prednisone

Hybrid View

  1. #1
    Join Date
    Oct 2008
    Location
    California
    Posts
    1,213
    Thanks
    280
    Thanked 208 Times in 162 Posts

    Default Indications For Meds Other Than Prednisone

    I've had an increase in joint pain, but attributed it to, ahem, getting older. Oh, and picking up the golf clubs after a year. I saw Handsome Rheumy today who wanted me to continue a low dose of daily Prednisone for joint swelling/pain. I told him I'd rather not do that due to long term side effects. We compromised with him prescribing Naprosyn 500 mg daily, maximum of three per day.

    Then, Handsome Rheumy invited me to return on October 31 to see how I'm doing. If no improvement, we'll discuss MTX and Cellcept. Sure, I'll slap down my co-pay to see Handsome Rheumy again! LOL

    What are your experiences with MTX and Cellcept? Why were they prescribed for you? How long before you noticed an improvement?

    I tried to read the "It's M Day" thread, but it's way too long (on an iPhone).

    Thanks for your input!

  2. #2
    Join Date
    Mar 2011
    Location
    pinjarra, western australia
    Posts
    2,955
    Blog Entries
    1
    Thanks
    1,412
    Thanked 1,641 Times in 1,127 Posts

    Default

    When I was first diagnosed, my rheumy put me on plaquenil and pred.

    The pred was to work fast, whilst waiting for the plaquenil to take its effect.

    After a few months we started to reduce the pred. As the pain and symptoms started to come back ..... then we started mtx.
    We started on 2mg on 1 day per week. The dosage was increased as required, as the pred was reduced also. I ended up on 20mg of mtx.
    After about 1 1/2 years we cut mtx back, now at 10mg.

    My understanding is that pred works quickly and comes out of the system quickly to. There is no " build up" of the medication required.
    Mtx does require a build up in our system. It is only a couple of weeks. but it is a build up.

    Also mtx is a disease modifying drug.
    This means it actually creates a chemical reaction within our system.
    My un-doctor description is it is like making a cake.
    mix flour, butter and an egg together, and you make a new mixture that can never be separated again. (mtx does this in our system.)

    hopefully I have made sense to you.
    Last edited by steve.b; 09-17-2013 at 03:05 AM.
    When you're stressed, You eat Ice cream, Cake, Chocolate & Sweets. Why? Because stressed spelled backwards is DESSERTS.

  3. The Following 3 Users Say Thank You to steve.b For This Useful Post:

    BonusMom (09-17-2013), redstringsoul (11-26-2013), tgal (09-17-2013)

  4. #3
    Join Date
    Oct 2008
    Location
    California
    Posts
    1,213
    Thanks
    280
    Thanked 208 Times in 162 Posts

    Default

    Thanks Steve! I can always count on my WHL family to give me the info I'm looking for in an easy to understand manner (and making/baking a cake is an excellent analogy BTW, especially for someone who LOVES to bake!).

  5. #4
    Join Date
    Nov 2011
    Posts
    466
    Thanks
    314
    Thanked 317 Times in 192 Posts

    Default

    I have had great luck with Mtx so far (been on it maybe a year and a half or so...). I take 10mg on Monday nights and 10mg on Thursday nights...that works best for me. It does take a while to get used to, but for me side effects faded to almost nothing by about 8-10 weeks. I take daily folic acid to battle side effects, and it works. Some people can't handle taking it orally (too much nausea) and they use injections, which I hear are easy...but as I said, I have almost no side effects at all. I always take it on a full stomach, at night, so I sleep through any queasiness or fatigue - and I wake up the next morning feeling good!

  6. The Following 2 Users Say Thank You to SleepyInSeattle For This Useful Post:

    BonusMom (09-17-2013), tgal (09-17-2013)

  7. #5
    Join Date
    Jul 2011
    Location
    suburban chicago
    Posts
    342
    Thanks
    230
    Thanked 121 Times in 96 Posts

    Default

    I have been on all 3-Imuran,MTX and currently Cellcept in addition to Plaquenol and Prednisone.
    I have tolerated all meds well-no side effects to speak of but I can't really say anything other than the Plaquenol and Prednisone have made any appreciable difference.
    My daily pain is pretty constant-always there but more or less tolerable.
    I get my labs done every 2 months and I have consistently high anti-ds-dna levels which none of the 3 meds seem to help.

  8. The Following User Says Thank You to n.mac For This Useful Post:

    BonusMom (09-17-2013)

  9. #6
    Join Date
    Oct 2008
    Location
    California
    Posts
    1,213
    Thanks
    280
    Thanked 208 Times in 162 Posts

    Default

    Quote Originally Posted by n.mac View Post
    I have been on all 3-Imuran,MTX and currently Cellcept in addition to Plaquenol and Prednisone.
    I have tolerated all meds well-no side effects to speak of but I can't really say anything other than the Plaquenol and Prednisone have made any appreciable difference.
    My daily pain is pretty constant-always there but more or less tolerable.
    I get my labs done every 2 months and I have consistently high anti-ds-dna levels which none of the 3 meds seem to help.
    Bummer n.mac! I just abhor taking Prednisone. I understand they aren't intended for long term use and Handsome Rheumy understands (and appreciates) my not wanting to take them on a long term basis. But, that means taking something on a regular basis, which stinks, too.

    I wish you had better luck with Imuran, MTX and/or Cellcept.

    I haven't had elevated CRP in a while and I don't recall if my Anti-DS-DNA was ever positive.

    It'll be interesting to see what my recent labs show since Handsome Rheumy found my joints swollen and I didn't think much of it.

    Thanks for sharing your experience.

  10. #7
    Join Date
    Oct 2008
    Location
    California
    Posts
    1,213
    Thanks
    280
    Thanked 208 Times in 162 Posts

    Default

    Thanks for sharing your experience, SiS.

    Many people complain of similar complaints with Plaquenil, but it's never bothered me either. I take my dose at night just for the reason you describe. I would probably try what you do, or maybe try Friday and Tuesday since I still work and would want to see how my body reacts and, hopefully, not miss much work.

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •