So far as I'm aware, I'm the first person in my family to be diagnosed with SLE but my cousin has started to have issues with the joints of her hands (and some other symptoms similar to mine) and the possiblity of Lupus has been mentioned.
That said, my Grandmother's brother passed away in his teens from 'Rheumatics in the Legs' which I believe is what's stated on his Death Certificate and to me I guess that could possibly be Lupus related although we also have Muscular Dystrophy in our family (my brother has MD) so could just as easily have been that too as they obviously didn't know all that they know now about either disease.
Numpty:- (num-p-tee) dialect, chiefly Scot, ~n. 1. a bumbling fool: one who is intellectually challenged. 2. widely known in Scotland as an MSP (Member of Scottish Parliament).