The ANA is a diagnostic tool that helps rheumys who suspect a certain illness to narrow it down.Certain patterns are seen only in certain illnesses.the ANA alone being positive without any other symptoms,labs or markers at a low titer would likely not cause a second glance as it can be found in healthy individuals with no other AI issue.These people dont go on to develop any AI illness and a false positive becomes more common as we age.
The titer is how many times the collected blood must be diluted until no abnormalities are noted once you get to the point where there are none the last dilution is your number.This is done by DOUBLING the number.
1st dilution would be 1:40
2nd dilution would be 1:80
3rd dilution would be 1:160
4th dilution would be 1:320
5th dilution would be 1:640
6th dilution would be 1:1280
7th dilution would be 1:2560
As to the specifics of the centromere I am not familiar with it.I know the ANA can fluctuate,can change pattern as I have been both speckled and homogenous at two different testings.
The higher the ANA the greater likelihood that there is something AI going on.It sounds like you have a good dr who is listening,waiting to label you until further testing and narrowing of possibilities can be done.You cant really ask for more honestly.
Hope you find out answers soon and Welcome!
SLE w/Sjogrens Overlap and Raynaud's diagnosed in 2007.Fibro in 2009.
The Early Bird May Get The Worm But the Second Mouse Gets The Cheese.