Titers are only checked when positive. Basically they tell you HOW POSITIVE the results are. If the ANA is negative the testing goes no further. Please keep in mind though, that some Lupus specialists do not believe in checking ANA after a Lupis diagnosis and 1 positive result is in the file. There really is no need and we all know our bloodwork changes all the time. Sadly, too many docs want to remove a diagnosis when the positive ANA turns negative but that is because the are idiots!