For me, just the necessary "slowing down" from all this stuff has been enough to make my muscles go weird on me. If you were active at all before, you will have issues with "muscle atrophy" as you slow down. I have to almost force myself to just get up and move and do my "core" exercises. I do have to skip the "bad" days, and not over-do things when I feel better. Do what you can for exercise... Similar symptoms also go with fibromyalgia. I've had EMGs, and other tests for symptoms similar to yours. That said, they've tried me on lyrica and a couple other similar meds, and though I don't like the effect, I'm pretty sure it'd just be a matter of finding a good balance with the docs' help. Other folks do have CNS issues from lupus.