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Thread: Started Methotrexate last night....

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    Question Started Methotrexate last night....

    Hello all. I hope you are well. I had my Rheumy appointment yesterday and she said my latest labs showed disease activity. My ana was the highest titer it's ever been with a homogenous pattern. My complements have continued to stay low and dip as well. I have been on prednisone for over a year and not been able to come off of it. My Rheumy seems to think it's due to a combination of all 3 factors including Adrenal Insufficiency, Steroid Withdrawal and Lupus Inflammation I currently have small ulcers and fatigue but this was before starting the metho last night..... So....she has left me on 7.,5mg of Prednisone and Added 2 2.5mg Pills a week for 3 weeks and then 3 2.5mg pills a week after I get the blood levels done when the first 2 weeks are completed. I'm also on Folic Acid 1mg/day which my Rheumy said helps with side effects.

    Can I get some input on the med and how it has affected others? It's hard to believe we are treated with chemo/cancer drugs. I've even read they use it for ectopic pregnancy. I have severe photosensitivity already and am allergic to chemicals in sunscreen so i cannot use any of it. Any ideas on how the hair loss and nausea will be? Anything anyone wants to say about it is welcome!

    Take care and God Bless!

    -Lupie LadyBug
    *LadyBug*- Epilepsy Dx: 2003 & UCTD w/SLE features Dx: 2009 SLE/Lupus Dx: May 12th 2011--Current Meds:
    Plaquenil-200mg 2x/day
    Prednisone-7.5mg 1x/day
    Methotrexate- 2.5mg 4 pills 1x/week
    Keppra-750mg 2x/day
    Daily Vitamin-1x/day
    Folic Acid- 1mg 1x/day
    Protonix 40mg 1x/day
    Bentyl- 10mg 4x/day, Miralax- 17g 1x/day
    Vit. D 800IU's 1x/day
    Lyrica- 75mg 1x/day
    Flonase 50mcg 2 sprays each 1x/day

    Wanna know my story, just ask!

    *Lord_Walters_Lady* <3

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    Hey there. I found that taking it at night helps with the upset stomach. The stomach issues get better after your body gets used to it though. I had to come off of it for a couple of weeks and I dealt with it again. It really isn't bad. It is not near as bad as I was scared it would be. After the first few weeks at full dose, if you take it at night, you will hardly notice it
    Mari

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    The only nausea I had happened within the first 2 weeks of starting the medication. I would take my weekly dose (6 2.5mg) on Saturday night then I'd get the nausea on Sunday. Never anything too bad and the rest of the week I wouldn't have any. The hair loss I wasn't too thrilled about. I already had really fine hair to begin with, so any kind of hair loss was quite noticeable to me. My rheumy increased my Folic Acid from 1mg/day to 2mg/day and he also put me on 5mg leucovorin that I take once a week. (Leucovorin is a Folinic Acid, which is a type of Folic Acid). I still have some hair loss, but not nearly as bad as I used to.

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    Britt,
    I used to take MTX. My stomach would not tolerate the pills at all, but I did fine on the injections. I didn't notice any hair loss at all. We take much lower doses than cancer patients take.
    Check through the archives for a thread called "It's M Day". That thread is full of great information, and it really helped me.
    Hugs,
    Marla

    Found it! http://forum.wehavelupus.com/showthr...seedeadmonkeys
    Last edited by magistramarla; 04-11-2012 at 09:08 PM.

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    some helpful information i was told.

    never take folic acid on mtx day.

    both drugs create chemical reaction in our body.
    but the reaction from folic acid interferes with mtx.

    i have recently cut down my mtx to 10mg.
    but i am still on 5mg of folic acid 6 days a week.

    in australia they offer a 10mg dosage of mtx.
    it is called methoblastin.
    we also have 2.5mg.

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