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Thread: And the results are in....

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    Exclamation And the results are in....

    Well, PCP is calling it a Lupus/Sclerdoma overlap.

    I had an elevated ANA (1:320), a high RNP antibody (172 with 100-120 being normal) and a high SCL-70 antibody (195 with 100-120 being normal)

    What irks me is my ANA pattern came back as speckled AND homogenous. Can anyone shed some light?


    Thes results have been a long time coming. As hard as it is to process, it's also somewhat of a relief.
    "Rule number one is, don't sweat the small stuff. Rule number two is, it's all small stuff."
    -Robert Eliot

    Dx: Potential Lupus, Diffuse Systemic Sclerosis, Mixed Connective Tissue Disease

    Rx: Prednisone 5mg 1x daily, Lyrica 75mg 2x daily, Omeprazole 200mg 1x daily, Xanax .5mg prn

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    Quote Originally Posted by tripLexie View Post
    Well, PCP is calling it a Lupus/Sclerdoma overlap.

    I had an elevated ANA (1:320), a high RNP antibody (172 with 100-120 being normal) and a high SCL-70 antibody (195 with 100-120 being normal)

    What irks me is my ANA pattern came back as speckled AND homogenous. Can anyone shed some light?


    Thes results have been a long time coming. As hard as it is to process, it's also somewhat of a relief.

    We all understand the relief part. While you don't want to be sick you do want to be validates and start meds to help.

    The majority of people with Lupus have multiple AI diseases or "overlapping" diseases. All this means is that you are in the same boat as the majority. Sorry you are sick but I am glad you will get the treatment you need
    Mari

    Success is not final, failure is not fatal: it is the courage to continue that counts.

    ~Winston Churchill~







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    saysuzie has a good explenation on speckled and homogenous.
    i cannot remember the explanation properly.
    but do not worry about it.

    hopefully she will read this soon and enlighten you.

    i am glad you have a name for your pain.
    i am glad effective treatment can begin.
    i am not glad you are ill.

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    tripLexie (02-23-2012)

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    The different patterns point to different AI diseases. Those, along with symptoms and other testing, allow the doctor to make a diagnosis

    • Homogenous (diffuse) - associated with SLE and mixed connective tissue disease
    • Speckled - associated with SLE, Sjogren syndrome, scleroderma, polymyositis, rheumatoid arthritis, and mixed connective tissue disease
    • Nucleolar - associated with scleroderma and polymyositis
    • Centromere pattern (peripheral) - associated with scleroderma and CREST (Calcinosis, Raynaud's syndrome, Esophogeal dysmotility, Sclerodactyly, Telangiectasia)
    Mari

    Success is not final, failure is not fatal: it is the courage to continue that counts.

    ~Winston Churchill~







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    steve.b (02-23-2012), tripLexie (02-23-2012)

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