Anti-Dsna antiboides (anti-double stranded antibodies) are specific to Lupus (they are not commonly found in any other auto-immune disorder than Lupus). Once the body has produced the antibody, it will never go away. However, the levels can be treated with medications (one of which is Methotrexate).
Autoantibodies seen in lupus are directed against nuclear antigens such as nucleosomes, DNA, and histone proteins that are found within the body's cells and plasma. Autoantibodies are involved in disease development either by forming immune complexes that lodge in our organs, disrupting our normal organ function, or by cross-reacting with targeted antigens and damaging our tissue.
Targets of autoantibodies are usually the nuclear and cytoplasmic macromolecules, lipid components, and plasma proteins. The most frequently associated autoantibodies in SLE include smith (Sm), nucleosomes, histones, and double stranded (ds) DNA. Anti-ds DNA antibodies are the most frequently detected antibodies in Lupus.
Your doctor may be a bit confused because you Anti-dsDna levels are high, indicating that Lupus is definitely present. However, your other labs are normal and you are saying that you are doing OK. So, he is thinking that you do have Lupus, but you are not showing or relating any other indicators of Lupus. So he has to rely upon what you tell him and he feels that your are not feeling as well as you say that you are. So, he is attempting to assure that your symptoms do not worsen. To do this, he is prescribing medications that may help to lower the levels of your Anti-dsDna and to (hopefully) prevent future symptoms.
It sounds to me as if this doctor is A KEEPER. What you must do now is to keep a log of everything that you experience (health-wise) and pay close attention to any symptom that you may be feeling. When he calls to ask how you are feeling, he is looking for any indication that other symptoms are present, which would require early treatment in order to keep them from worsening. So, be totally honest and very specific with him the next time that he inquires about how you feel.
Do as he says, continue to take your meds and contact him immediately if your symptoms change or if new ones appear. His confusion and concern are an effort to treat you quickly and appropriately and to know exactly what this illness is doing to your body. He is apparently a doctor whose primary concern is to treat you and to make sure that you are getting relief from any symptoms; rather than a doctor who says "well, your other tests are normal, so there is nothing wrong with you. Go home and take some Aspirin or see a psychiatrist because you must be making all of this up!"
I hope that I have answered your question. Please let me know if you need any thing further.
Peace and Blessings