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Thread: How long does MTX stay in the body?

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    Default How long does MTX stay in the body?

    Just got a call from my rheumy, no MTX again tonight, because my liver enzymes are even higher than they were last week.
    One week ago he told me not to take the shot, for one week, then take another bloodtest and we go from there. Well the liver enzimes have almost doubled from the week before, even though, I didn't take my shot last tuesday. Today would be my M-Day, but can't take it again.
    Does anyone know, how long MTX stays in the body, because I am already starting to have more pain.
    Or is it in my head?

    Debbie
    I may have been dealt a bad hand, but at least I'm still playing with a full deck. ( most of the time anyway).

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    I have not been able to find any information that gives a specific amount of time that MTX remains in the body. Most articles talked about the absorption rate and the variables for the absorption rates. I would venture to say that, since the dosage is weekly, it is assumed that the medication remains within the body for at least seven days.
    I have heard many MTX users state that when they no longer take the MTX, many of their symptoms begin to worsen or re-appear. So, you are not alone in feeling this way. I wish that I had better information for you and I do hope that you start to feel better soon. Please keep us posted on how you are doing and know that we are here to help you as much as we can.

    Peace & Blessinga
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    Saysusie
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    Thank you, Susie.
    I thought maybe the pain is all in my head, because I haven't taken my shot for two weeks now.
    It is frustrating, when you finally found something that helps and now you have to stop taking it.
    Had an Ultra Sound done today, from the liver, gallbladder, spleen, kidneys, aorta and pelvic. I hope to hear something soon.
    My bloodpressure is still high 149/102. I guess that means something is going on.

    Debbie
    I may have been dealt a bad hand, but at least I'm still playing with a full deck. ( most of the time anyway).

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    I think it depends on each individual. Be patient and listen to the doctor. I was told in July to stop a d just the past two weeks I feel myself sliding. But It is always best to follow the docs advice.

    Hope you feel better
    Hugs
    Nonna

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    Well, its tuesday again, my M-day, but got a call from the rheumy again, no go on the shot tonight. Because liver enzymes are still up. The last shot I had was four weeks ago.
    I am feeling the pain and other symptoms returning.
    My ultra sound results were good, but I still have a slight pain in my upper abdomen and a really weird feeling, like something is protruting, from the inside out. But it is not visible on the outside. For all the moms here, it feels like a baby moving in your tummy, but it is higher, right under the ribs.
    I have an appointment with the rheumy on 9/14, next wednesday. He said we are going to have to change the meds and find something else that will work for me.
    I am so frustrated and in pain again.

    Debbie
    I may have been dealt a bad hand, but at least I'm still playing with a full deck. ( most of the time anyway).

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    FYI, it's now 2 months I'm off the MTX. I'm in extreme pain again. My appointment is next Wednesday. I can't wait.

    Hugs nonna

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