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  1. Multidrug, multitarget regimen results in higher remission rates for lupus nephritis

    A multidrug, multitarget regimen proves superior to intravenous cyclophosphamide (IVCY) as induction therapy for lupus nephritis (LN), according to a randomized, controlled trial being published...
  2. Study suggests altering gut bacteria might mitigate lupus

    Lactobacillus species, commonly seen in yogurt cultures, correlate, in the guts of mouse models, with mitigation of lupus symptoms, while Lachnospiraceae, a type of Clostridia, correlate with...
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  3. Potential treatment for lupus with more natural compounds that have fewer side effect

    New findings by a biomedical engineer and his team at the University of Houston (UH) raise hope for a new class of drugs to treat lupus that may not include the long list of adverse risks and side......
  4. Plant-derived compound 'may effectively treat lupus with fewer side effects'

    Researchers from the University of Houston, TX, say a plant-derived compound called CDDO halted development of lupus nephritis in mice and produced no significant side effects.

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  5. Invasive kidney biopsy for lupus patients may be replaced by math model

    Mathematics might be able to reduce the need for invasive biopsies in patients suffering kidney damage related to the autoimmune disease lupus.

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  6. Harnessing the power of lupus antibodies for use in targeted cancer therapy

    Yale Cancer Center researchers may have discovered a new way of harnessing lupus antibodies to sabotage cancer cells made vulnerable by deficient DNA repair.

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    Personalised medicine for lupus

    Medical researchers have used DNA sequencing to identify a gene variant responsible for causing lupus in a young patient.

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  8. Misdiagnosis common in rheumatologic diseases like lupus

    Lupus and other rheumatologic diseases can initially present as neurological disorders such as headaches and seizures, and thus delay diagnosis for many months, according to Loyola University...
  9. 1 in 6 lupus patients readmitted to the hospital within a month of discharge

    A new study finds that among patients with the most common form of lupus - systemic lupus erythematosus - 1 in 6 are readmitted to the hospital within 30 days of being discharged.

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  10. In the quest for safer treatment for systemic lupus erythematosus

    The treatment of systemic lupus erythematosus has traditionally been based on glucocorticoids administered orally.

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  11. Lupus exacerbated when Anti-dsDNA, surface-expressed TLR4 and endosomal TLR9 cooperat

    Systemic lupus erythematosus (SLE) is a complicated multifactorial autoimmune disease influenced by many genetic and environmental factors.

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  12. Stopping immunosuppressants in lupus: new guidance on how and when

    A new study presented at the European League Against Rheumatism Annual Congress (EULAR 2014) showed that, for the majority of lupus patients who are in remission, it is possible to successfully...
  13. Class, ancestry and medication are factors in cardiac risk for lupus patients

    New research published in Rheumatology, the international, peer-reviewed scientific journal, has suggested that systemic lupus erythematosus (SLE) patients of African descent and from lower...
  14. Function restored in T cells from lupus patients by targetting lipid metabolism

    Patients with the autoimmune disorder lupus erythematosus (SLE) exhibit multiple immune system defects.

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  15. Pregnancy complications in lupus patients may be prevented by malaria drug combo

    An anti-malaria drug combination might be useful in helping to prevent pregnancy complications in women with lupus and the related disorder antiphospholipid syndrome, Yale School of Medicine...
  16. New hope for lupus screening and treatment

    Researchers from the University of Alabama at Birmingham (UAB) have discovered a new immune protein influencing autoimmune diseases such as lupus and multiple sclerosis.In autoimmune diseases like...
  17. Wide disparities in diagnosis time for childhood lupus identified

    New research has found that a child's symptoms and the doctor they are referred by can affect the time taken to diagnose juvenile systemic lupus erythematosus (JSLE). The research, which shows...
  18. Lupus patients may benefit from identification of targets of autoantibodies

    Patients with the autoimmune disease systemic lupus erythematosus (SLE) produce autoantibodies that target can cause damage to multiple organ systems. The host factors that are targeted by...
  19. Nontoxic therapy shows encouraging results in blood samples from lupus patients

    Northwestern Medicine® scientists have successfully tested a nontoxic therapy that suppresses Lupus in blood samples of people with the autoimmune disease. This is a positive step toward one day...
  20. Headaches in lupus patients not linked to disease activity study says

    Headache is common among patients with system lupus erythematosus according to new research published in Arthritis & Rheumatism, a journal of the American College of Rheumatology (ACR). The study...
  21. Lupus a greater risk for young, black women with more life-threatening complications

    Young, black women have the highest rate of developing lupus and are most likely to be diagnosed at a younger age than whites and during childbearing years, according to a new University of Michigan...
  22. How DNA damage may trigger lupus erythematosus

    Summer, sun and the sea - a dream vacation for most - can turn sour for those affected by lupus erythematosus. For them, absorption of the UV-light component in sunlight may cause florid inflammation...
  23. Gene variants identifed that may cause kidney problems in lupus patients

    Variants in a particular gene are linked with an increased risk for kidney complications in patients with lupus, according to a study appearing in an upcoming issue of the Journal of the American...
  24. OGT Marks World Lupus Day With Announcement Of Novel Biomarker Panel To Support Earli

    Superior sensitivity and specificity compared to current laboratory tests Oxford Gene Technology (OGT), provider of innovative genetics research and biomarker solutions to advance molecular medicine,...
  25. In Development - A Nanogel-Based Treatment For Lupus

    Systemic lupus erythematosus (SLE) is disease in which the immune system mistakenly attacks healthy tissues, resulting in inflammation and tissue damage. Current treatments are focused on suppression...
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