View Full Version : Anti-nuclear antibodies always bad news?

03-25-2011, 11:21 PM
I'm trying to get my head around this ANA thing. Is it always a bad thing to have these antibodies? My test came back as positive speckled pattern 1:640; so it basically means I have these antibodies that are potentially harming my body? Does everyone have these antibodies? What makes them appear? Are they always harmful?

Sorry for all the questions. I would just like to know what made them appear in my body apparently out of nowhere. I've been feeling extremely tired and run down the past few years, this is the first time I've had this test done.

What were your ANA results? My doctor said I'm on the high side of normal. I haven't been diagnosed with anything, but I've been referred to a specialist doctor.


03-26-2011, 12:18 AM
From what I've read, a healthy person can have those antibodies in response to an infection, so its not always bad news.
The speckled pattern can also be significant. SaySusie knows much more about this than me, or you might check the stickys - I'll bet that there are some good explanations there.

My ANAs have fluctuated between 1:8 and 1:16. There are lots of other tests for AI diseases that the rheumatologist will order. For example, SSA and SSB. This can help with diagnosing SLE and/or Sjogren's. I also tested positive for RA and Psoriasis. There are tests for dry eyes that the ophthalmologist can do that indicate Sjogren's. I've also had the lip biopsy that was positive for Sjogren's.

Hopefully, you will find a good rheumy who will check for lots of things and then decide where to go from there. You're just at the beginning of this. Don't get too worried - just learn all that you can, keep good records and keep asking questions, both here and at the docs.
Good luck, and keep us informed.

03-26-2011, 06:30 AM
I was told when mine came back as a speckled pattern it means more that one ai diease. Bonita

03-26-2011, 07:37 AM
Yes, you can have a positive ANA and be fine. It just means that they need to look farther. I also want to say that there are people with Lupus that have such mild case that a dose of plaquenil may be all they need.

@Bonita.. I have never heard that. I will have to look into that one.

03-26-2011, 07:45 AM
don't be so concerned about the ana a perfect healthy person can have a positive ana if there is AI in the family. That alone doesn't mean that you have anything bad. It is the whole picture that counts. Symptoms and all the bloodwork together will make the diagnosis. Try not to worry or be stressed it only makes thinks worse on you.

03-27-2011, 05:30 PM
Hello Katina,
Marla is quite right at points she's stated i've got an high ANA but you do need to see a specialist and get furthur tests done to actually see what's happening and i hope goodness comes out of your results.

Hugs Terri xxx