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Katina
03-23-2011, 11:49 PM
Hey guys I'm new to the forum. I'm a little worried because I heard back from my doctor today, I had a blood test last week for an array for tests, liver, urea, electrolytes, CBC, glucose, Iron, ANA just to name a few. I went back today for the results and all tests were perfectly normal except for my ANA which is Positive Speckled Pattern (Titre 1:640) with a note saying 'No fhx of AI disease and clinical exam did not reveal any unusual stigmata of the SLE'. I have been referred to a Medical Physician.

Does anyone know what this could mean? I understand a positive result could be the cause of a number of types of autoimmune disorders, and can also be positive for no reason.

Any advice would be greatly appreciated.

lovehubby
03-24-2011, 07:11 AM
If you have any family members with AI they say you can run a positive ANA but be fine. So other then that I don't know! But how do you feel? do you have any other problems like joint pain fevers or rashes? Are you tied all the time do you have any thyroid problems? because thyroid peoblems can cause you to run a positive ANA if it is Hashimotos thyroiditis ! Good Luck and Take Care
Michele

Katina
03-24-2011, 07:38 AM
If you have any family members with AI they say you can run a positive ANA but be fine. So other then that I don't know! But how do you feel? do you have any other problems like joint pain fevers or rashes? Are you tied all the time do you have any thyroid problems? because thyroid peoblems can cause you to run a positive ANA if it is Hashimotos thyroiditis ! Good Luck and Take Care
Michele

Thanks for the reply, Michele :)

I don't have any family history of autoimmune diseases (that I know of). The reason my dr ordered the test was because for around the past 2 years I've felt tired constantly and never seem to have any energy. I also have frequent headaches (almost every day), occasional skin rashes mainly on my arms, and since the age of 10 I've been losing my hair, it's not too noticeable but it's thinned quite a lot and I'm forever picking it up off the floor in large amounts. My thyroid tests came back normal.

Katina

Katina
03-24-2011, 07:39 AM
P.s how high is an ANA level of 1:640? slightly high, moderate etc?
thanks

tgal
03-24-2011, 08:21 AM
Hi There and welcome to WHL! If you read through other posts you will hear us say often that "there is not a test for Lupus" and that is true in your case as well. A lupus diagnosis is made when several things come together. A list of these can be found on a Sticky in the Newly Diagnosed section. Just because you have that positive blood tests doesn't mean you have lupus. In order to get a lupus diagnosis at least 4 of the 11 diagnosis have to be met. To answer your questions about how high is 1:640 the answer is that it is high enough to consider lupus or autoimmune diseases but it is not many have a higher result.

Hope this answered your question and try not to worry!

Saysusie
03-24-2011, 02:56 PM
In laymen's terms, your doctor has basically said that, even though you have a High ANA with a speckled pattern (usually found in almost all Lupus patients), none of your other tests point to Lupus. "Stigmata" is a medical way of saying "bodily marks" (which I assume may refer to rashes, ulcers, redness, etc.). So, essentially you have no bodily marks that are common to Lupus, none of the other lab works indicates Lupus, but you do have a high ANA which (as you know) can be caused by other conditions.
Now, your doctors ARE NOT supposed to stop here and dismiss you. However, too many of them do. What they are supposed to do now is to continue to run tests in order to determine exactly what is causing your symptoms, especially in light of the High ANA. There are some tests that are more specific to Lupus (even though there is NO test that can or cannot diagnose Lupus alone) that your doctors should consider if they are thinking that Lupus may be the culprit.
Please do read the stickys in "Newly Diagnosed" as well as in the other forums in order to find out what some of those other tests are.
Also, if you have any questions at all, please feel free to come to us and we will do all that we can to answer them for you.
I wish you the very best!

Peace and Blessings
Namaste
Saysusie

Katina
03-24-2011, 05:28 PM
thank you all for your replies, tips and information. My doctor has referred me to a specialist. Hopefully I won't have to wait too long to get in. I just noticed on my ANA report it says, 'Anti Nuclear Antibodies in this range (1:160-1:640) are only significant in patients with a clinical history of SLE or other autoimmune disease. Suggest anti dsDNA and ENA testing only if clinically indicated.

Like I said before, I don't have any family history of AI. So it's probably nothing, and they may only want to repeat the ANA to see if it's returned to normal? I have a slight cold at the moment, could this in any way interfere with the ANA result? Maybe a false positive?

Thank you all again for being so kind and answering my questions

Katina

Katina
03-24-2011, 06:04 PM
I've looked up the symptoms of diseases commonly associated with a positive speckled pattern; Lupus, Scleroderma, Sjogren's, etc. I have none of the symptoms. Is it possible that the ANA has detected the presence of a disease in its very early stage and I'm yet to develop symptoms? Has anyone had a similar experience? I know I shouldn't been reading too much into this positive result, and am aware a positive reading can be found in perfectly healthy individuals. It's just hard and a little confusing.

ritzbit
03-24-2011, 06:26 PM
Don't completely dismiss the results because you don't have any family history of AI diseases. I don't either. I had some of the really vague symptoms like fatigue for a really long time before I had any visible symptoms. I developed Raynauds which lead me to a Rheumatologist thinking that she would tell me to dress warm just like my family doctor. Blood tests came back and my ANA was 1:1600. We caught mine early and I went awhile before having any other problems. Look into it fully before you dismiss it as being nothing because if it is something you could treat it now and prevent it from ever turning into something bad.

tgal
03-24-2011, 07:37 PM
Anything is possible but there are other things besides autoimmune issues that cause a positive ANA.

What does a positive ANA result mean?

ANAs are found in patients who have various autoimmune diseases, but not only autoimmune diseases. ANAs can be found also in patients with infections, cancer, lung diseases, gastrointestinal diseases, hormonal diseases, blood diseases, skin diseases, and in elderly people or people with a family history of rheumatic disease. ANAs are actually found in about 5% of the normal population.

The ANA results are just one factor in diagnosing, and must be considered together with the patient's clinical symptoms and other diagnostic tests. Medical history also plays a role because some prescription drugs can cause "drug-induced ANAs".

Hope that makes you feel better

Katina
03-24-2011, 08:00 PM
So I have an appointment with a medical physician on May 6. I'll let you know what happens.
Thanks again to everyone for all the help.

Katina