View Full Version : Protein in urine?

04-14-2009, 09:12 PM
Ok... I am already on plaquinel 400 mg daily, naproxen 500 twice a day and 7.5mg prednisone a day.

Started to get intermitent flank pain. Doc ordered Urinanalysis. I have protein in my urine. Not a whole lot 20 mg/dl where normal on the lab page says 0-9 mg/dl is in a more normal range.

I am not sure what this means. Obviously I am still not feeling well. What does this mean if anything at all?



04-14-2009, 10:34 PM
I have that too. But nothing been done for it yet. When they found the protein next they ran a 24 hour urine test. To see how much protein I was spilling. And then they checked my creatinine level. But now I'm having some of the symptom you watch out for. Foamy urine and swelling. I plan to go to a Renal Dr. soon But this has been going on a long time. I getting frustrated waiting on my doctors to do something.

04-15-2009, 12:17 AM
Im a little worried about my urine test. When i last went into the doctor they tested it straight away. The nurse came into the room and spoke to my doctor and kept pointing to a number on this piece of paper. Then my doctor just stuck it into my file. I know i should have asked what it was but i was a little shocked and worried. My doctor tries to sugarcoat things for me which is kinda good cause i tend to get really worked up over things. I suppose if there was anything to be really worried about i would have been informed. I can only wonder now i guess...

04-15-2009, 04:47 AM
protein in my urine was actually one of the first signs that showed that i might have had lupus, when i was going thru my diagnosis.
i haven't really been affected by it...because my protein levels were also low. [[not sure the numbers tho]] but i know that my rheumy has me go to a nephrologist. first, right at diagnosis. and i had to do a 24 hour collection, then 3 weeks later, i went back and did the same thing again. and since my numbers havent changed at all....he made the period longer. now i dont have to see him until june 1st. but everytime i go to my rheumy, they still do a urine sample to make sure my protein levels havent gotten higher since my last nephrologist visit. i could be wrong, but i believe that methotrexate also helps with renal problems, along with trying to ween away from predinsone.
but i could be wrong.
i take both ...haha

but yeah most likely, you will have to see a nephrologist. but dont worry, its not too bad :]

04-15-2009, 05:10 AM
In 2005 i was told i had protein in urine and couldn't get life ins. policy until they found out what was wrong. well after more symptoms i have lupus.

the protein has always been in my urine so now after being tested every year my doc is sending me to a uralogist. she also maybe get a ct scan of kidneys and they found a stone in jan. which has still not passed.

you need to go to a urilogist (SP) brain fog bad.
they will help you the best for this symptom.:wacko:

04-15-2009, 06:34 AM
hi cami,

i recently went through some kidney issues, and here is what i found out:

A nephrologist is the specialist that treats kidney problems.

My kidney blood work showed borderline kidney function, plus i was having flank pain, and blood in my urine. The nephrologist had some tests run, plus i did the 24 hour urine catch.

he said lupus nephritis (lupus of the kidneys) is not painful, and yes my kidneys are a concern, but he feels we can keep a close watch, and we will have plenty of time to respond if necessary. I go to him every three months, and he rechecks everything.

The dr. said he thinks the pain in the flank is because the lupus is attacking the soft tissues around the kidney. But the kidney itself is ok.

we have some members with the lupus nephritis diagnosis, and i am sure they will be along to ease your concerns.

04-15-2009, 04:48 PM
Thank you all

04-16-2009, 09:39 AM
Protein in the urine is an indication that there may be kidney involvement with your Lupus. Kidney involvement in lupus rarely causes discomfort or pain (like kidney stones or infection). This is the most common kidney problem in Lupus -protein leakage in the urine. This can be mild and detected only on testing, or severe gradually leading to a lowering of the protein level in your blood (a low albumin level). When this happens there is a tendency for your ankles to swell, for you to have fluid retention and to have general fluid bloating.
If you are losing protein in the urine ('proteinuria'), then the amount will need to be quantified. For this, most doctors order a 24-hour urine collection. All the urine over a full 24-hour period is collected and the precise amount of protein lost over this period is measured. A sample of the urine is also sent to a laboratory for analysis for bacteria and for a microscopic examination.
Normal urine under the microscope is clear but when there is inflammation anywhere in the urinary tract (in the kidneys or the bladder) cells are present, either red cells or white cells. More important is the presence of clumps of cells called 'casts'. These clumps are indicative of kidney inflammation rather than a bladder inflammation and is of vital importance in the diagnosis and assessment of kidney involvement in Lupus.

When the kidney is inflamed the blood pressure frequently rises and blood pressure measurement is one of the important parts of the physical examination of lupus patients. When the kidney is more severely damaged its normal filtering process is grossly impaired and toxic elements such as urea and creatinine, normally present in the blood in small amounts, build up leading to weight loss, nausea and general malaise.

If your doctor finds that there is kidney inflammation, a combination of steroids and an immunosuppressive medicine is usually prescribed. For active or severe kidney disease, the most widely used immunosuppressive is cyclophosphamide given intermittently by injection. In the olden days cyclophosphamide was given as a tablet but this produced more side-effects and most doctors have now converted to giving intermittent 'pulses'. This comes in the form of a drip given into the vein, usually given weekly for three weeks then monthly for 3-12 months. Doses vary from clinic to clinic, but the more modern fashion has been to use lower doses than those previously used and this has the benefit of far less side-effects.
A milder immunosuppressive that is often used is azathioprine. This is given as tablet-form usually at a dose of about 2’mg/kg body weight.
All immunosuppressives can affect the blood count and regular blood counts will be done regularly if you on taking these meds.
Other immunosuppressive drugs such as cyclosporin-A are also being used increasingly, however, the two mainstays of treatment remain cyclophosphamide and azathioprine.

I hope that this has been helpful! I wish you the best!
Peace and Blessings

04-16-2009, 11:22 AM
Thank you

It was very helpful

04-18-2009, 12:12 AM
i have Lupus Nephritis and i'm currently taking 2,500mg of CellCept (an immunosuppressant) for it. my blood tests currently show no sign of a decrease in kidney functioning.

i was diagnosed after a urinalysis, a 24 hour collection (both showed large amounts of protein), and a renal biopsy. my rheumatologist referred me to a nephrologist for opinions on all these and on my treatment. after being on CellCept for 2 months, my rheumatologist ordered another 24 hour collection. the results of this one showed that my protein levels were decreased by half.

even though i went through all of this, not once did i ever experience any pain or noticeable symptoms. i never would have known i had kidney inflammation if it wasn't for all these tests.