View Full Version : question abt kidney involvement
05-09-2005, 07:32 AM
Are Lupus patients more prone to kidney infections?
And what about the discoid rash, can that appear around the hairline in the temple area?
05-10-2005, 10:34 AM
Lupus damages parts of the body because antibodies travel in the blood stream and get trapped in the tissues of the body, causing local damage (called glomerulonephritis). The kidneys have a large blood supply, and the filters of the kidneys are very delicate, so it is not surprising that the kidneys are affected in some cases. However, it is not possible to predict whether a particular individual with Lupus will get Lupus in the kidneys. About 1 in 3 people with Lupus will get kidney disease at some time in their life. Sometimes kidney disease is the first sign of Lupus, sometimes kidney disease only develops after Lupus has been present for some years.
The most important kidney disease is glomerulonephritis, which is inflammation in the filters of the kidneys. There are several types of glomerulonephritis in Lupus. These have been put into 5 categories by the World Health Organisation, and a specialist can predict the long term outcome of kidney disease by knowing which type of glomerulonephritis someone with Lupus has, and how badly the kidney is affected by that type. In addition to glomerulonephritis, Lupus patients can get kidney infections and a condition associated with anti cardiolipin antibodies (also called anti-phospholipid syndrome).
Lupus can be a serious disease in some people, but more often it continues for many years, causing problems without causing death. In 100 people with Lupus:-
70 people will not get kidney disease
20 people will get troublesome but not serious kidney disease
8 people will get kidney failure, some will need dialysis
2 people will get severe kidney failure and a Lupus crisis (see next section)
About the Discoidal Rash; skin problems are very common in lupus and many different types of problems can occur. Discoid lupus is a type of lupus that tends to be confined to the skin and other organs in the body are not involved. Discoid lupus occurs in patches across the body. These patches tend to be well defined, thickened and scaly, they are slightly red in colour and can itch. The appearance can vary between people and also on different areas of the body on the same person. As the patches heal they tend to leave scars and on darker skins the pigment in the skin can be lost leaving white areas. If discoid lupus occurs on the scalp the hair will be lost as the patches heal leaving permanent bald areas.
Lupus lesions can result in several forms of hair loss (alopecia). Systemic lupus patients who have been severely ill with their disease may (over a period of time) develop a transient hair loss in which large amounts of hair evolve into a resting phase and fall out. However, this is quickly replaced by new hair. In addition, a severe flare of systemic lupus erythematosus can result in defective hair growth which causes the hair to be fragile and to break easily. The hair is broken off above the surface of the scalp, especially at the edge of the scalp, giving the characteristic appearance termed "lupus hair".
In addition to losing hair because of discoid lesions, some lupus patients may develop a temporary, generalized hair loss followed by the growth of new hair. Hair loss may also be caused by infection or by use of corticosteroids or other lupus medications. A severe lupus flare could result in defective hair growth, causing the hair to be fragile and break easily.
I hope that I have answered your questions. Let me know if you need more information :P
Peace and Blessings
05-10-2005, 09:47 PM
Thanks so much for your information! I really have gotten so much more info here than at the doc's. :roll:
I meant also to ask if you were familiar with "blood bumps"? I get them here and there and they are very small bumps that seem to be blood- filled.
They don't itch though....thankfully! :P
Is there a medical name for these bumps?
05-11-2005, 05:22 PM
Hi Sandfeet :lol:
Other than the common skin rashes (such as the butterfly) common to Lupus, many of us get what is called "Non-specific" rashes. These are rashes which are also seen in diseases other than lupus, but they are extremely common in people with SLE. We may develop a red blotchy rash similar to the rash caused by a number of viruses, and similar to the rash caused by a variety of drugs (so-called drug-rash). These blotches may or may not be elevated and may be pink or red. They generally are found on the face, chest, back, and upper arms, and may or may not be itchy. This type of rash disappears quickly when we are treated with corticosteroids for our other lupus complaints.
Vasculitic rashes are seen frequently in people with SLE, especially in those of us who are acutely ill. These rashes are "non-specific" because they may be present in patients who do not have lupus. For example, a small number of individuals with rheumatoid arthritis develop vasculitic rashes. There are a wide variety of rashes due to vasculitis, including: tender bumps in the tips of the fingers or toes; rashes that look like splinters under the nailbeds; ulcers that form around the ankle joints or on the legs; and tender red bumps on the shins.
Some lesions in people with lupus, such as hives, may be due to inflammation of the small vessels of the skin.
Other non-specific lesions include nail bed redness and redness of the palms of the hands. Rarely, blisters due to lupus may be present.
Aren't we lucky to have so many different manifestations of SLE??? But, your bumps are not uncommon and I am glad that they do not cause you to itch!!
Best Of Luck