View Full Version : Skin Biopsy

03-10-2009, 12:23 PM
Was suggested we see a dermatologist for a skin biopsy. Does anyone know the accuracy of ruling in or out lupus from a biopsy?

thank you

03-10-2009, 04:40 PM
Hi Silentscream!

From what i know there is no exact test or biopsy of anything that for sure says "Lupus". With this illness attacking every part of your body its about keeping on top of what the problems are and making sure they dont get worse. Its constant monitoring. Our bodies can (and usually do) show symptoms from head to toe. Thats why there are so many specialists involved along with your GP who is supposed to monitor it ALL. Unfortunately its a difficult illness that can kick in other illnesses on top of one another. Make sure your daughter is charting EVERYTHING and she needs to notice ANY change in her body even if its little because it can turn BIG quick I know this from my own experiences.

Good Luck and my heart goes out to you and your daughter.

03-10-2009, 05:25 PM
In the beginning when I was first being diagnosed, the skin biopsy was one test in the whole package that they used to help determine my diagnosis. They used it in conjunction with all my lab work to help make a definitive diagnosis.

Unfortunately, I was in a teaching hospital and they sent a couple of students in to do the test, and they chose to do it on my face. Found out later when my doc came to see me, that they could have done it on my arm or my butt. My doc was pretty pissed. That's when my doctor told me to always ask questions...and if it didn't seem right that they were doing a test on my face...ask them to call the ordering doctor first to make sure. I was pretty young then....I've learned a lot along the way since I was 18, unfortunately the hard way sometimes.

I do know that my skin biopsy did help them to rule in Lupus.

It sounds to me like your daughter's doctor is being thorough in searching for a diagnosis.



03-10-2009, 05:31 PM
Wow Lori, im glad you posted that because there are so many contradictory statements from drs. and patients ive met. Thats good information but im sorry for what you had to go through! Poor thing!!!

03-10-2009, 07:59 PM
I had four to five skin biopsies and then they ran all the labwork. It helps them make a definitive diagnosis. Hang in there.


03-11-2009, 02:00 PM
They should do two skin tests , one in an area of exposure to sun - say arms and one without exposure like buttocks.

A confluent stain with all five proteins implies a greater than 99 % probability of having SLE; if four proteins are present, a 95 % probability; three proteins an 86 % probability; & two proteins a 60 % probability provided that IgG is one of the proteins.

Pretty definitive really.

Avoid the face biopsy as previously mentioned.