View Full Version : Your thoughts in Chemo....
01-30-2009, 07:42 PM
well then I found some articles the other day about chemo therapy
apparently it is possible to sorta re-boot the immune system and replace the stem cell...
It is done in China and the patient fully recovered from Lupus....
I am not sure about all this but I wonder how come that for more than 50 years no cure for lupus has been found and yet something like this shud be possible....
Is it because it is not cost effective enough or.... ??
anyway was just wondering how far people have looked into this and what your thoughts are on this subject.....
02-02-2009, 03:27 AM
02-02-2009, 11:45 AM
I haven't researched much on chemotherapy for Lupus, but I must say I'm skeptical about someone recovering fully from Lupus since there is no cure as yet.
I've spent so many years getting my hopes up for the miracle cure, something that will make it go away, and after many, many disappointments, I just don't do it to myself anymore.
I have tried every well meaning 'cure' my neighbors, friends and family have brought to me, have tried various diet changes, all to no avail. Now I just try to do all the right things my body needs to maintain as healthy a person as I can.
Don't get me wrong.....I still hope for the 'cure', and I hope it happens during my lifetime so I get to see it. I am so hoping that in the future others won't have to suffer with this horrible disease, but I'm waiting to hear about it from my Doctor when it does.
Sorry I couldn't be of more help with the Chemo question.
Hope your day is good. :D
02-02-2009, 12:37 PM
I found this article from John Hopkins -
Now lets talk about chemotherapy, the gold standard for the worst lupus. Are there other ways to give chemotherapy, so you wouldn't have to give it once a month for six months and then for two more years every three months? An oncologist at Hopkins studied a disease called aplastic anemia, where the blood counts are so low the person has to have a bone marrow transplant. He asked, for the people who survived the transplant and did very well, whose immune system did they have? The donor's or their own? It turns out all the long term survivors had their own immune system. They hadn't been cured by the bone marrow transplant. The hypothesis is they were cured by the chemotherapy given before the bone marrow transplant. The oncologist gave the chemo for four days in a row and then never again. This oncologist decided to start treating aplastic anemia with four days of chemotherapy instead of doing bone marrow transplants. In the next 10 patients treated just with chemotherapy, seven out of 10 had a complete remission. Three did die of the aplastic anemia, but no one died of the four days of chemotherapy.
Now, these oncologists then asked me if perhaps they had a cure that might work on lupus. How can you go from aplastic anemia to lupus? Aplastic anemia is one of those localized autoimmune disorders, like thyroid disease. It's an autoimmune problem in just organ systemthe bone marrow. I wondered if any of my patients would die from the chemotherapy. They said it was highly unlikely because the white blood cell count is low for only about 14 days. During that period, the person is at risk for infection, but never again. So, for the last six years we've been testing four days of chemotherapy. The bad news is, not everyone goes into a remission. The good news is 40% do, and the remissions have lasted as long as five years!
An example, a patient with terrible kidney disease had four days of chemotherapy. Over the next 18 months, she gradually improved to the point where her lupus was in complete remission. She had a successful pregnancy. Now, of the 60% of the people who don't go into complete remission, half are much better. We've lowered their lupus burden, but we haven't gotten rid of it. Then, there are 25% of patients who have the same level of lupus activity. This is not a cure, but it's another way of thinking about the worst lupus.
the system won't let me post the link becasue I'm new but it is hopkins-arthritis (dot) org
02-07-2009, 09:04 PM
which doc wrote this? It sounds promising.
Has anyone been to JH for treatment?
02-09-2009, 02:39 AM
I am on a form of chemotherapy.......methotrexate. When someone with cancer is on chemo they have to avoid people with colds and other stuff because it brings their immune system down sooooo low.Our immune systems are soooooo over active that with the help of chemo the immune system will lower to a normal level and allow our bodies to function at a normal pace. The side effects are yucky but bearable if you are seeing some relief :wink: I would ask your doctor about it if you are interested, it might just help!
02-09-2009, 03:03 AM
mmmm will do....
I am going to the lupus specialist clinic soon so we'll see from there.....
Thanks for the input on the subject.....