11-09-2007, 11:02 AM
i just had my periodical tests for sle. This time not only do i have positive ana, ssa-ro, preteinuria and red cells in urine + proteine but also a positive ANCA antibodies. i haven't seen my doc yet....do you know what this could be about???
11-09-2007, 11:14 AM
now I have to look through my records to see if ive had that test
too dad gum many tests to keep track of :x :x :x :x
11-09-2007, 06:38 PM
ANCA antibodies = antineutrophil cytoplasmic antibodies
Antineutrophil cytoplasmic antibodies (ANCA) are present in several vasculitides disorders such as Wegener granulomatosis, Churg-Strauss syndrome, microscopic polyangiitis and idiopathic necrotizing and crescentic glomerulonephritis (Vasculitides is the plural of the word vasculitis, which may be used to describe any disorder characterized by inflammation of the blood or lymph vessels. It can affect any type or size of blood vessel—large arteries and veins as well as arterioles, venules, or capillaries).
Also, a number of connective tissue diseases (such as Lupus) have been found to have symptoms similar to the vasculitides. These are a class of antibodies identified by immunofluorescence. In general, serologic testing for ANCA is recommended for patients with: Glomerulonephritis, pulmonary hemorrhage, especially Pulmonary-Renal syndrome, Cutaneous vasculitis with systemic features, Connective Tissue Diseases (CTD's), Mononeuritis multiplex or other peripheral neuropathy, Long standing sinusitis or otitis, Subglottic tracheal stenosis, Retro-orbital mass.
Patients with vasculitis tend to have higher c-ANCA and p-ANCA titres.
It appears that your doctor is being very thorough, this is not a test that is routinely run to diagnose Lupus, but it can tell your doctor if other things are also going on!
I hope that I've been helpful :lol:
Peace and Blessings