View Full Version : question, just curious.

10-30-2007, 06:20 AM
I've read that its not that uncommon to have more than one auto-immune disease. It listed some common combos. I was wondering, can a person have Lupus and MS? Lupus seams to have so many other auto-immune problems with it. I just read that its believed MS is an auto-immune disease as well. It occured that I never seen it comboed with anything else. Its hard to diagnose, more less a process of elimation too (just more tests that can help with dx). MS problems listed some similar symptoms, just none about joints. I don't know why it bothers me :? , just a nagging in my brain to know if a person can have both.

10-30-2007, 10:44 AM
Hi Cheryl,

In my opinion, lupus is one of the most difficult diseases to diagnose because it does share so many similarities with other diseases. Saysusie will be by to share alot more information with you. She's a wealth of information when it comes to lupus information.

Because I have CNS lupus in addition to everything else, there are many of the same neurological symptoms that MS describes and so it took a very long time for my diagnosis. My only words of advice to you would be to research, ask lots of questions, and make sure that you have a doctor that you like. This has been one of the most important things I have done for myself. Lupus symptoms vary from mild to life-threatening and there is no cure - so, you'll have a long relationship with your lupus doctor. Having one that you like and trust is paramount to managing life with this disease.

I wish you the best, my prayers are with you. I would like to encourage you to stay plugged in to I HAVE LUPUS, there are lots of great people with a lot of information to share.

Take care & much love,

10-30-2007, 11:03 AM
MS is an autoimmune disease of the central nervous system (CNS). The body's own immune system attacks the myelin sheaths and axons, causing inflammation and scarring (thus multiple sclerosis - multiple scars). When enough axons and nerves are damaged, the messages carried by the nervous system are disrupted, causing the symptoms of MS.
Fibromyalgia means pain in the muscles, ligaments and tendons - the fibrous tissues in the body.
Lupus is a widespread and chronic autoimmune disease that causes the immune system to attack the body's own tissue and organs, including the joints, kidneys, heart, lungs, brain, blood or skin. Approximately one third of patients with lupus also develop fibromyalgia.
Now, about the possibility of having Lupus and MS; The disorders overlap clinically with symptoms and lab results. Both are autoimmune disorders, both are chronic disorders andboth are treated with steriods.
Some doctor feel that they both have a common etiology (causes or origin), however, this has never been proven. In Lupus, you can have multiple lesions in the central nervous system "white matter" that may parallel the activity of the underlying disorder or levels of the autoantibodies. By the same token, between 5 and 10 percent of Lupus patients have ANA or anti DSDNA antibodies without any evidence of SLE. On MRI, the lesions of SLE appear similar to the plaques of MS. In both, the optic nerve, brain or spinal cord may be involved leading to a variety of symptoms based on the location of the lesions. SLE also has a relapsing/remitting course which is also characteristic of MS.
Pathology of the "lesions" show that in SLE, the lesions represent small zone of infarct secondary to a small vessel vasculitis or embolism rather than the demyelination (the destructive removal of myelin, an insulating and protective fatty protein which sheaths nerve cells (neurons) characteristic of MS.
The joint and skin rash are typically found in SLE, but not in MS. The overlap between the two diseases in symptoms, course, and lab is significant. MS can happen to a patient with lupus and usually, depending on which of the two problems is more active and creating more problems, your neurologist will prescribe the treatment of the MS, and your rheumatologist will prescribe the treatment for lupus. However, there are many cases in which the medicines for one condition can also help the other (such as steroids), but it will take coordination between both specialists and it's important that you protect yourself by making sure that each of your doctors knows what treatments you are taking. There are some medications that might want to be avoided in your own situation that could aggravate another underlying problem.
MS & lupus are both autoimmune diseases, & you can have both together, but they are diagnosed & treated in different ways. Lupus can sometimes mimic the symptoms of MS, so it is essential that you get a diagnosis for both!

Peace and Blessings

10-30-2007, 08:19 PM
Thanks for the info. I know the info could have been eventually found on the web, but I'm still learning the art of using the right words. I knew someone here would more than likely know the answer I was looking for. I was curious for the info because it was one of the auto-immune diseases. Docs are always listing off possabilities, but never an answer. I have new symtoms. My eyes have been bothering me, mainly the right. I've been a little dizzy too. I read of the similarities, but noticed lupus effects joints and MS doesn't. MS can effect eyes more than lupus. I'm mainly joint pain, then muscles, then everything else. I've already been down a dx road 3x now. Just trying to learn as much as I can and be better informed this time around. Starting with a new Rhuemy doc and I don't want my strings pulled. I want to go in knowing more than I did last time. Thanks for easing my curious mind. :D