View Full Version : new treatments / new medications
10-31-2006, 02:58 PM
Is anyone interested in starting a new forum or maybe just a new msg thread about new treatments / new medications that are going on. I know there are some trials coming up and on-going for some promising treatments. Here are some articles I've come accross lately.
10-31-2006, 03:56 PM
It's always good to know that the pharmaceutical companies are working on the issue. Just remember it's usually several years from clinical trials to a drug being available on the market, and many drugs never make it past stage III clinical trials. Even "accelerated" drug approval for life threatening diseases can take about 2 years, for most drugs the process takes more like six. Even the anti-cancer drug Gleevec, which got accelerated approval, still took three years to make it through the whole process and many insurers still won't pay for it because of the cost involved.
The really frustrating thing is the extent to which treatment is dictated by insurers and not doctors! I know several people, including me, have had their insurers deny coverage for Rituxan. So even promising treatments available now may not be accessible for many people.
11-10-2006, 11:53 AM
11-13-2006, 12:57 PM
ZymoGenetics and Serono Report Detailed Positive Results From Atacicept Phase 1b Clinical Trial in Patients With Lupus
11-14-2006, 03:44 PM
This is great stuff. I will post anything interesting that I find. I never seem to find the good stuff though.
I feel encouraged that the biologics for SLE are just around the corner.....I have also tried Rituxan and its the best thing yet to help me. It didn't put me in remission but things are definitely more manageable.
Keep up the great research.
11-18-2006, 08:16 PM
Zymogenetics sponsored a great Lupus Symposium through our LFA chapter that I went to almost a year ago. They gave us a great breakfast and lunch, parkign and everything in Seattle (and it wasn't to push their drugs - just donated).
Anyway, I thought it was cool. Nice to see big business doing good stuff, too......like finding new treatments!
01-12-2007, 12:06 PM
Verto to begin trials on Lupus treatment:
01-22-2007, 11:41 AM
Scientists Spot Key Autoimmune Disease Genes:
Scientists link 30 genes to multiple sclerosis and other autoimmune diseases:
01-22-2007, 06:56 PM
Wow - this seems very encouraging. Thanks for the great research.
02-14-2007, 11:41 AM
Some good news.
HGS, Glaxo Phase III Lupus Trial Underway
02-28-2007, 11:48 AM
An interesting finding regarding lupus and depression.
03-12-2007, 12:02 PM
La Jolla Pharmaceutical Announces Positive Interim Antibody Results From Riquent(R) Lupus Phase 3 Trial
03-12-2007, 03:12 PM
This is all such wonderful information and really promising. Would you all like me to ask Conrad to place a new forum here for "Promising reasearch, medications, Treatments and New Information"? Or should I just move all of these to the "Lupus Website Links" forum?
06-08-2007, 07:24 AM
Sorry I haven't posted in a while. Here are some of the interesting articles that I've come accross lately.
Aspreva lupus treatment fast-tracked by FDA (CellCept)
HGS begins second Phase III trial for lupus drug (LymphoStat-B)
La Jolla reveals data supporting safety of lupus drug (Riquent)
Genes Add Up Risk Of Autoimmune Disease
New Website Broadcasts Urgent Need for Lupus Clinical Trials
Methods for treating lupus nephritis
06-14-2007, 10:51 AM
Human Genome's Drug Shows Lupus Activity (LymphoStat-B)
06-19-2007, 12:39 PM
At Long Term Follow-Up Over OneThird Of Refractory Lupus Patients Remain Stable (Rituxan)
06-20-2007, 10:36 AM
Treatment With Belimumab (LymphoStat-B) Showed Improvement In Symptoms In 46 Percent Of Lupus Patients At 52 Weeks
07-20-2007, 01:02 PM
MedImmune Advances Potential Treatment For Patients With Lupus
Malaria drugs cut cancer risk in lupus patients
08-02-2007, 06:32 AM
Astion's lupus drug to receive orphan status (ASF-1096)
Genetic Mutations Linked To Lupus
Interferon-alpha levels may predict who might be at risk to develop lupus
08-02-2007, 08:50 AM
Don't forget to also add these links to "Lupus WebSite Links".
Good Looking Out and thank you for always sharing your research with us :lol:
Peace and Blessings
08-16-2007, 08:25 PM
Study Reports Epratuzumab Affects B-Cells from Patients With Lupus in a Unique Manner
Preclinical study suggests organ-transplant drug may aid in lupus fight - Rapamune (sirolimus/rapamycin)
08-24-2007, 02:56 PM
Have We Uncovered A New Form Of Lupus?
09-07-2007, 07:08 AM
New Risk Gene For Rheumatoid Arthritis And Lupus Opens Door To More Effective Treatments
09-09-2007, 09:12 PM
has anyone heard of "HAELAN 951"? a friend just mentioned it where they're doing trials with it on lupus patients and helping them deal with the effects of chemo (cytoxan, etc....).
09-24-2007, 07:21 AM
Genetic Cause Discovered For Systemic Lupus Erythematosus
10-02-2007, 07:36 AM
Experimental Lupus Vaccine Prolongs Life of Mice With Lupus
10-02-2007, 03:28 PM
Haelan is an health product that claims to provide a full spectrum of nutritional components that are not contained in the normal food supply. Haelan's fermented soybean beverages are supposedly and excellent source of predigested soy proteins and is used for those who are suffering from malnutrition due to poor assimilation of foods or the toxic side-effects of chemotherapy and/or radiation treatments. There is not much about its use for Lupus other than it claims to boost the immune system for atuo-immune diseases.
Thant's all I know about it. Most of the websites dealing with Haelan are sites hosted by Haelan, so I don't know how honest or objective their information would be
Peace and Blessings
10-04-2007, 07:02 AM
ZymoGenetics and Merck Serono Receive FDA Special Protocol Assessment for Atacicept Pivotal Study in Lupus Nephritis
10-08-2007, 07:06 AM
New cancer drugs could help in autoimmune disease
10-29-2007, 08:24 AM
Coley Pharmaceutical Group Diversifies Pipeline with First-in-Class TLR Antagonist for the Treatment of Systemic Lupus Erythematosus
10-29-2007, 07:24 PM
Very interesting....... The article did not state if the subject dosed was human or a test animal. Anyway, the first dose was today, I'm very interested in seeing what happens in a month from now.
As always....thank you for the great information and thank you for always doing the research!
Peace and Blessings
11-12-2007, 08:09 AM
Targeted Treatment Strategies For Lupus Suggested By Research
Treatment Of End-Stage Renal Disease In Lupus Using Existing Drugs
Fish Oil May Be Good Supplemental Treatment For Lupus, Study Suggests
Therapy Effective For Reducing Lupus Flares
Human Genome Reports Positive Lupus Data
11-27-2007, 08:20 AM
Dynavax Reports Progress In Lupus Program With Inhibitor Of TLR7 And TLR9
12-13-2007, 07:33 AM
ZymoGenetics and Merck Serono Initiate Phase 2/3 Clinical Trial of Atacicept in Lupus Nephritis
12-16-2007, 03:48 PM
New Approach For Attacking Lupus Identified
Molecular 'Trip Switch' Shuts Down Inflammatory Response
01-02-2008, 07:53 AM
Two Genes Are Important Key To Regulating Immune Response - Findings Have Implications For Research Into Lupus, Cancer And HIV/AIDS
01-03-2008, 07:45 AM
Protein's New Role Discovered In Autoimmune Disease
01-08-2008, 07:54 AM
Anthera Pharmaceuticals Acquires AMG 623
01-18-2008, 02:16 PM
Discovery Of New Genetic Mutation That Halts The Development Of Lupus
Completion Of Phase Ib Clinical Study Of TRX1 for Lupus
ZymoGenetics Announces Special Protocol Assessment for Atacicept in General SLE
New Way To Block Destructive Rush Of Immune Cells Found
01-20-2008, 10:41 AM
Wouldn't it be wonderful if they did, indeed, discover a gene that predisposes us to Lupus and then find treatment that targets that gene.....thereby finding a cure!
Pooie95....I truly appreciate the research that you continue to do. Thank you so much!!
Peace and Blessings
01-25-2008, 12:35 PM
DNA Variations Signal Lupus Risk
01-30-2008, 07:14 AM
High Time for HiCy
Accentia Biopharmaceuticals Announces that Revimmune is Profiled in Hopkins Medicine Magazine
02-11-2008, 12:47 PM
La Jolla Pharmaceutical Company Reports Progress in International Phase 3 Riquent(R) Study
02-14-2008, 03:35 PM
Overabundance of Immune Cells Might Trigger Lupus
06-30-2009, 01:22 PM
Positive Long-Term Data For BENLYSTA (formerly LYMPHOSTAT-B(R)) In Patients With Active Lupus
HGS Hoping to Survive Final Test of Lupus Drug
Key Culprits In Lupus Discovered
Novel DNA Vaccine Leads To Kidney Damage Prevention In Systemic Lupus Erythematosus Models
Anxiety and depression common with lupus
07-20-2009, 06:54 AM
07-20-2009, 07:03 AM
i was just reading research information about Benlysta....it has passed the first stage trials with 53.6 % accuracy in reducing lupus symptoms. It is in the second trial period which should be completed in November. If approved, this would be the first drug designed specifically for the treatment of lupus.
07-20-2009, 09:27 AM
Also an article on this in USA today - today:
Also Wall Street Journal, Washington Post, Business week (interesting it's all business and financial publications that are a-buzz instead of health and medical publicaitons...)
"The study was designed to determine whether patients taking the drug achieved a favorable response on three stringent measures of lupus severity. Lupus is a complex disease that waxes and wanes, with flare-ups caused by antibodies that attack the brain and other organs.
About 1.5 million people in the USA have lupus.
Benlysta fights these naturally occurring antibodies with man-made antibodies. Because the digestive tract would break Benlysta down, the drug must be taken intravenously in one-hour outpatient sessions, once a month.
08-27-2009, 06:15 AM
09-01-2010, 12:11 PM
That's very, very interesting. Thanks for posting the link.
That is sooooooooo interesting! Two of the tests that are causing my doctors such confusion are my Factor VIII and Factor IX blood test. Those test basically tell alot about your blood and they can't figure out why mine is so thick! It is one of those tests they have just tossed off to the side and not worried with. This may explain it!
09-06-2010, 08:59 PM
The blood thinner stuff *is* very interesting. It would seem to make sense, since a lot of folks with lupus throw clots.
I don't know if I like the idea of knocking a person's immune system down, like the other thread points to... There's a few other drugs that do that, and for me, with an already comprimised IgG & IgM system, that doesn't seem like a good idea to take things down further...
What *really* gets me is the company's stock price went up by 50%, and the side-effects are kind of fluffed over... lol
Now, for a guy, I find *this* interesting:
as linked to in the RSS feeds section...