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pooie95
10-31-2006, 02:58 PM
Is anyone interested in starting a new forum or maybe just a new msg thread about new treatments / new medications that are going on. I know there are some trials coming up and on-going for some promising treatments. Here are some articles I've come accross lately.

http://www.pharmabiz.com/article/detnews.asp?articleid=35824

http://uk.biz.yahoo.com/30102006/214/immupharma-delighted-lupus-drug-trial.html

http://abclocal.go.com/wls/story?section=health&id=4687910

MARYCAIN
10-31-2006, 03:56 PM
It's always good to know that the pharmaceutical companies are working on the issue. Just remember it's usually several years from clinical trials to a drug being available on the market, and many drugs never make it past stage III clinical trials. Even "accelerated" drug approval for life threatening diseases can take about 2 years, for most drugs the process takes more like six. Even the anti-cancer drug Gleevec, which got accelerated approval, still took three years to make it through the whole process and many insurers still won't pay for it because of the cost involved.

The really frustrating thing is the extent to which treatment is dictated by insurers and not doctors! I know several people, including me, have had their insurers deny coverage for Rituxan. So even promising treatments available now may not be accessible for many people.

pooie95
11-10-2006, 11:53 AM
Current Events:

http://www.eurekalert.org/pub_releases/2006-11/wfub-nbf110306.php

pooie95
11-13-2006, 12:57 PM
ZymoGenetics and Serono Report Detailed Positive Results From Atacicept Phase 1b Clinical Trial in Patients With Lupus

http://biz.yahoo.com/prnews/061113/ukf017.html?.v=2

kkelly
11-14-2006, 03:44 PM
Hey pooey95
This is great stuff. I will post anything interesting that I find. I never seem to find the good stuff though.
I feel encouraged that the biologics for SLE are just around the corner.....I have also tried Rituxan and its the best thing yet to help me. It didn't put me in remission but things are definitely more manageable.
Keep up the great research.
Karen

Missy
11-18-2006, 08:16 PM
Zymogenetics sponsored a great Lupus Symposium through our LFA chapter that I went to almost a year ago. They gave us a great breakfast and lunch, parkign and everything in Seattle (and it wasn't to push their drugs - just donated).

Anyway, I thought it was cool. Nice to see big business doing good stuff, too......like finding new treatments!

pooie95
01-12-2007, 12:06 PM
Verto to begin trials on Lupus treatment:

http://www.globes.co.il/serveen/globes/docview.asp?did=1000171482&fid=1725

pooie95
01-22-2007, 11:41 AM
Scientists Spot Key Autoimmune Disease Genes:

http://news.yahoo.com/s/hsn/20070122/hl_hsn/scientistsspotkeyautoimmunediseasegenes


Scientists link 30 genes to multiple sclerosis and other autoimmune diseases:

http://www.msnbc.msn.com/id/16738416/site/newsweek/

kkelly
01-22-2007, 06:56 PM
Wow - this seems very encouraging. Thanks for the great research.
K

pooie95
02-14-2007, 11:41 AM
Some good news.

HGS, Glaxo Phase III Lupus Trial Underway

http://www.redorbit.com/news/health/839060/hgs_glaxo_phase_iii_lupus_trial_underway/index.html?source=r_health

pooie95
02-28-2007, 11:48 AM
An interesting finding regarding lupus and depression.

http://www.healthcentral.com/newsdetail/408/602233.html

pooie95
03-12-2007, 12:02 PM
La Jolla Pharmaceutical Announces Positive Interim Antibody Results From Riquent(R) Lupus Phase 3 Trial

http://biz.yahoo.com/prnews/070308/lath046.html?.v=88

Saysusie
03-12-2007, 03:12 PM
This is all such wonderful information and really promising. Would you all like me to ask Conrad to place a new forum here for "Promising reasearch, medications, Treatments and New Information"? Or should I just move all of these to the "Lupus Website Links" forum?
Saysusie

pooie95
06-08-2007, 07:24 AM
Sorry I haven't posted in a while. Here are some of the interesting articles that I've come accross lately.

Aspreva lupus treatment fast-tracked by FDA (CellCept)
http://www.pharmaceutical-business-review.com/article_news.asp?guid=43C5BDFE-2554-4C7D-9369-08DC90ADAC57

HGS begins second Phase III trial for lupus drug (LymphoStat-B)
http://biz.yahoo.com/bizj/070531/1470685.html?.v=1

La Jolla reveals data supporting safety of lupus drug (Riquent)
http://www.pharmaceutical-business-review.com/article_news.asp?guid=2DC82D62-4029-4999-A3FB-8F9538AD7FF6

Genes Add Up Risk Of Autoimmune Disease
http://www.medicalnewstoday.com/medicalnews.php?newsid=71973&nfid=rssfeeds

New Website Broadcasts Urgent Need for Lupus Clinical Trials
http://biz.yahoo.com/prnews/070521/nym138.html?.v=78

Methods for treating lupus nephritis
http://www.news-medical.net/?id=25228

pooie95
06-14-2007, 10:51 AM
Human Genome's Drug Shows Lupus Activity (LymphoStat-B)

http://biz.yahoo.com/ap/070614/human_genome_sciences_lymphostat.html?.v=1

pooie95
06-19-2007, 12:39 PM
At Long Term Follow-Up Over OneThird Of Refractory Lupus Patients Remain Stable (Rituxan)

http://www.medicalnewstoday.com/medicalnews.php?newsid=74349&nfid=rssfeeds

pooie95
06-20-2007, 10:36 AM
Treatment With Belimumab (LymphoStat-B) Showed Improvement In Symptoms In 46 Percent Of Lupus Patients At 52 Weeks

http://www.medicalnewstoday.com/medicalnews.php?newsid=74362&nfid=rssfeeds

pooie95
07-20-2007, 01:02 PM
MedImmune Advances Potential Treatment For Patients With Lupus
http://www.medicalnewstoday.com/articles/77345.php

Malaria drugs cut cancer risk in lupus patients
http://news.yahoo.com/s/nm/20070719/hl_nm/malaria_drugs_cut_cancer_risk_lupus_patie_dc_1

pooie95
08-02-2007, 06:32 AM
Astion's lupus drug to receive orphan status (ASF-1096)
http://www.pharmaceutical-business-review.com/article_news.asp?guid=3E992632-F222-4FD4-9BCD-B3F97D9F481A

Genetic Mutations Linked To Lupus
http://www.sciencedaily.com/releases/2007/07/070730092501.htm

Interferon-alpha levels may predict who might be at risk to develop lupus
http://www.news-medical.net/?id=28223

Saysusie
08-02-2007, 08:50 AM
Pooie95:
Don't forget to also add these links to "Lupus WebSite Links".

Good Looking Out and thank you for always sharing your research with us :lol:

Peace and Blessings
Saysusie

pooie95
08-16-2007, 08:25 PM
Study Reports Epratuzumab Affects B-Cells from Patients With Lupus in a Unique Manner
http://biz.yahoo.com/pz/070816/125071.html

Preclinical study suggests organ-transplant drug may aid in lupus fight - Rapamune (sirolimus/rapamycin)
http://www.eurekalert.org/pub_releases/2007-08/usmc-pss081407.php

pooie95
08-24-2007, 02:56 PM
Have We Uncovered A New Form Of Lupus?
http://www.medicalnewstoday.com/articles/80471.php

pooie95
09-07-2007, 07:08 AM
New Risk Gene For Rheumatoid Arthritis And Lupus Opens Door To More Effective Treatments

http://www.medicalnewstoday.com/articles/81747.php

angela
09-09-2007, 09:12 PM
has anyone heard of "HAELAN 951"? a friend just mentioned it where they're doing trials with it on lupus patients and helping them deal with the effects of chemo (cytoxan, etc....).

thanks :)

pooie95
09-24-2007, 07:21 AM
Genetic Cause Discovered For Systemic Lupus Erythematosus

http://www.medicalnewstoday.com/articles/83175.php

pooie95
10-02-2007, 07:36 AM
Experimental Lupus Vaccine Prolongs Life of Mice With Lupus

http://lupus.webmd.com/news/20071001/new-vaccine-may-treat-lupus?src=RSS_PUBLIC

Saysusie
10-02-2007, 03:28 PM
Hi Angela;
Haelan is an health product that claims to provide a full spectrum of nutritional components that are not contained in the normal food supply. Haelan's fermented soybean beverages are supposedly and excellent source of predigested soy proteins and is used for those who are suffering from malnutrition due to poor assimilation of foods or the toxic side-effects of chemotherapy and/or radiation treatments. There is not much about its use for Lupus other than it claims to boost the immune system for atuo-immune diseases.
Thant's all I know about it. Most of the websites dealing with Haelan are sites hosted by Haelan, so I don't know how honest or objective their information would be
:?
Peace and Blessings
Saysusie

pooie95
10-04-2007, 07:02 AM
ZymoGenetics and Merck Serono Receive FDA Special Protocol Assessment for Atacicept Pivotal Study in Lupus Nephritis

http://biz.yahoo.com/prnews/071004/aqth133.html?.v=19

pooie95
10-08-2007, 07:06 AM
New cancer drugs could help in autoimmune disease

http://news.yahoo.com/s/nm/20071007/sc_nm/autoimmune_drugs_dc_1

pooie95
10-29-2007, 08:24 AM
Coley Pharmaceutical Group Diversifies Pipeline with First-in-Class TLR Antagonist for the Treatment of Systemic Lupus Erythematosus

http://biz.yahoo.com/prnews/071029/nem057.html?.v=26

Saysusie
10-29-2007, 07:24 PM
Very interesting....... The article did not state if the subject dosed was human or a test animal. Anyway, the first dose was today, I'm very interested in seeing what happens in a month from now.

As always....thank you for the great information and thank you for always doing the research!

Peace and Blessings
Saysusie

pooie95
11-12-2007, 08:09 AM
Targeted Treatment Strategies For Lupus Suggested By Research
http://www.medicalnewstoday.com/articles/88421.php

Treatment Of End-Stage Renal Disease In Lupus Using Existing Drugs
http://www.medicalnewstoday.com/articles/88405.php

Fish Oil May Be Good Supplemental Treatment For Lupus, Study Suggests
http://www.sciencedaily.com/releases/2007/11/071109202954.htm

Therapy Effective For Reducing Lupus Flares
http://www.medicalnewstoday.com/articles/88357.php

Human Genome Reports Positive Lupus Data
http://biz.yahoo.com/ap/071109/human_genome_sciences_study.html?.v=2

pooie95
11-27-2007, 08:20 AM
Dynavax Reports Progress In Lupus Program With Inhibitor Of TLR7 And TLR9

http://www.medicalnewstoday.com/articles/89828.php

pooie95
12-13-2007, 07:33 AM
ZymoGenetics and Merck Serono Initiate Phase 2/3 Clinical Trial of Atacicept in Lupus Nephritis
http://biz.yahoo.com/bw/071213/20071212005067.html?.v=1

pooie95
12-16-2007, 03:48 PM
New Approach For Attacking Lupus Identified
http://www.sciencedaily.com/releases/2007/12/071216155436.htm

Molecular 'Trip Switch' Shuts Down Inflammatory Response
http://www.sciencedaily.com/releases/2007/12/071213121017.htm

pooie95
01-02-2008, 07:53 AM
Two Genes Are Important Key To Regulating Immune Response - Findings Have Implications For Research Into Lupus, Cancer And HIV/AIDS
http://www.medicalnewstoday.com/articles/92768.php

pooie95
01-03-2008, 07:45 AM
Protein's New Role Discovered In Autoimmune Disease
http://www.sciencedaily.com/releases/2008/01/080102134118.htm

pooie95
01-08-2008, 07:54 AM
Anthera Pharmaceuticals Acquires AMG 623
http://www.centredaily.com/business/story/317289.html

pooie95
01-18-2008, 02:16 PM
Discovery Of New Genetic Mutation That Halts The Development Of Lupus
http://www.medicalnewstoday.com/articles/94465.php

Completion Of Phase Ib Clinical Study Of TRX1 for Lupus
http://www.medicalnewstoday.com/articles/94087.php

ZymoGenetics Announces Special Protocol Assessment for Atacicept in General SLE
http://biz.yahoo.com/bw/080115/20080115005084.html?.v=1

New Way To Block Destructive Rush Of Immune Cells Found
http://www.sciencedaily.com/releases/2008/01/080114082323.htm

Saysusie
01-20-2008, 10:41 AM
Wouldn't it be wonderful if they did, indeed, discover a gene that predisposes us to Lupus and then find treatment that targets that gene.....thereby finding a cure!

Pooie95....I truly appreciate the research that you continue to do. Thank you so much!!

Peace and Blessings
Saysusie

pooie95
01-25-2008, 12:35 PM
DNA Variations Signal Lupus Risk
http://www.medicalnewstoday.com/articles/94661.php

pooie95
01-30-2008, 07:14 AM
High Time for HiCy
http://www.hopkinsmedicine.org/hmn/W08/feature1.cfm

Accentia Biopharmaceuticals Announces that Revimmune is Profiled in Hopkins Medicine Magazine
http://www.wallstreet-online.de/nachrichten/nachricht/2251245.html

pooie95
02-11-2008, 12:47 PM
La Jolla Pharmaceutical Company Reports Progress in International Phase 3 Riquent(R) Study
http://biz.yahoo.com/bw/080211/20080211005434.html?.v=1

pooie95
02-14-2008, 03:35 PM
Overabundance of Immune Cells Might Trigger Lupus
http://news.yahoo.com/s/hsn/20080214/hl_hsn/overabundanceofimmunecellsmighttriggerlupus

pooie95
06-30-2009, 01:22 PM
Positive Long-Term Data For BENLYSTA (formerly LYMPHOSTAT-B(R)) In Patients With Active Lupus
http://www.medicalnewstoday.com/articles/153936.php

HGS Hoping to Survive Final Test of Lupus Drug
http://www.washingtonpost.com/wp-dyn/content/article/2009/06/28/AR2009062802457.html?wprss=rss_business

Key Culprits In Lupus Discovered
http://www.sciencedaily.com/releases/2009/06/090629200811.htm

Novel DNA Vaccine Leads To Kidney Damage Prevention In Systemic Lupus Erythematosus Models
http://www.sciencedaily.com/releases/2009/06/090611110952.htm

Anxiety and depression common with lupus
http://www.redorbit.com/news/health/1705939/anxiety_and_depression_common_with_lupus/index.html?source=r_health

pooie95
07-20-2009, 06:54 AM
http://www.medicalnewstoday.com/articles/158066.php

mountaindreamer
07-20-2009, 07:03 AM
i was just reading research information about Benlysta....it has passed the first stage trials with 53.6 % accuracy in reducing lupus symptoms. It is in the second trial period which should be completed in November. If approved, this would be the first drug designed specifically for the treatment of lupus.

karenboss
07-20-2009, 09:27 AM
Also an article on this in USA today - today:

http://www.usatoday.com/news/health/2009-07-20-lupus-benlysta-drug_N.htm

Also Wall Street Journal, Washington Post, Business week (interesting it's all business and financial publications that are a-buzz instead of health and medical publicaitons...)

quote:

"The study was designed to determine whether patients taking the drug achieved a favorable response on three stringent measures of lupus severity. Lupus is a complex disease that waxes and wanes, with flare-ups caused by antibodies that attack the brain and other organs.

About 1.5 million people in the USA have lupus.

Benlysta fights these naturally occurring antibodies with man-made antibodies. Because the digestive tract would break Benlysta down, the drug must be taken intravenously in one-hour outpatient sessions, once a month.

pooie95
08-27-2009, 06:15 AM
http://www.reuters.com/article/marketsNews/idINLR59606920090827?rpc=44

pooie95
09-01-2010, 12:11 PM
http://news.yahoo.com/s/nm/20100901/hl_nm/us_lupus_platelets_drugs_1

rob
09-01-2010, 02:49 PM
http://news.yahoo.com/s/nm/20100901/hl_nm/us_lupus_platelets_drugs_1

That's very, very interesting. Thanks for posting the link.

Rob

tgal
09-01-2010, 07:53 PM
That is sooooooooo interesting! Two of the tests that are causing my doctors such confusion are my Factor VIII and Factor IX blood test. Those test basically tell alot about your blood and they can't figure out why mine is so thick! It is one of those tests they have just tossed off to the side and not worried with. This may explain it!

jmail
09-06-2010, 08:59 PM
The blood thinner stuff *is* very interesting. It would seem to make sense, since a lot of folks with lupus throw clots.

I don't know if I like the idea of knocking a person's immune system down, like the other thread points to... There's a few other drugs that do that, and for me, with an already comprimised IgG & IgM system, that doesn't seem like a good idea to take things down further...

What *really* gets me is the company's stock price went up by 50%, and the side-effects are kind of fluffed over... lol

Now, for a guy, I find *this* interesting:
http://www.medicalnewstoday.com/articles/199965.php
as linked to in the RSS feeds section...