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ashleybaby715
12-08-2013, 12:43 AM
I had a few of my labs come in.

My BUN was higher than normal.
My sed-rate (which usually stays at like, 4) was 28
My Anti dsDNA (which i had no idea what it was) was 117.8 when the normal range is anything below 30.

When i googled about this, everything was pointing to Lupus Nephritis and it said that when you have a high anti dsdna, you have to get a kidney biopsy.

I have an appointment on the 16th with my rheumy to go over the results, and i'm scared he is going to tell me that i have to get one.
Has anyone ever gotten a kidney biopsy? If so, what is it like?

n.mac
12-08-2013, 09:12 AM
I have not had a kidney biopsy but I do have a chronically elevated anti ds-dna level and sed-rate .

The anti ds-dna test is very conclusive to lupus but does not necessarily indicate kidney or any organ involvement.

After I was first sent to see a ruhemy after a positive ANA result one of the first follow up lab tests that was performed showed my anti ds-dna level was 285
and now almost 3 years later last month I was at 135 and sed rate was 22. A few months ago it dropped to 98 but 2 months later it was back to 143.

How it was explained to me is that a positive ANA is indicative to an auto-immune disorder but anti ds-dna points directly to lupus.
They do keep a closer eye on my labs(full labs every 2 months regardless of how good I feel) but there is no indication of any kidney or any other organ involvement.

Niall

heather123
12-08-2013, 04:53 PM
Hi Ashley,
I have had the biopsy. The anti ds DNA antibody just means the disease is active right now. Hence, they are going to try to get that level down through corticosteroids, immunosuppressive s, or whatever. (With my initial kidney involvement I had a year and a half of chemo (cyclophosphamide) which was tough.

The biopsy is yet another experience. They gave me a sedative under the tongue so I was "awake". I was on the gourney (sp?) on my stomach and they just give you a needle that takes out the little piece of kidney.. A weird feeling but not too bad relative to a lot of other things I've been through with this disease!!!! Definitely not in my top 10 pain experiences. You will be good (wink face).

If you want to know anything else, feel free to ask. When do you get that done???

Smiles,
Heather

steve.b
12-08-2013, 06:04 PM
offering good thoughts, hope all is solvable.

LindaJ
01-05-2014, 07:53 PM
I had one or two done in my lifetime. They numb you and you don't feel anything but pressure. They did not put me under as I still remember this (I was only 16 and 19 and I am not 62). After they do this, you must stay in bed (hospital for me) and be sure not to move. The worst part of it for me was that my back began to ache without any movement! By the way, my kidney was being hurt by the Lupus. I continued normal life until age 42. I then got a kidney transplant. and now I continue to live normal life !! Don't fear....you are in God's hands always.

LindaJ
01-05-2014, 07:57 PM
Wow! Thank-you for the clarification of the ANA vs dsDNA! I recently got test results showing both! The ANA was 116 which I thought was really high since my last one was 11, and my dsDNA was negative which I thought was great! I have had Lupus for 48 years and I have had a kidney transplant (20 years now). I have been so worried since I found out about the ANA....do you know if that number is very high. My doctor never even contacted me about the results so that better be an ok number or I should look for another doctor!